翼状胬肉切除联合准分子激光治疗性角膜切削术与角膜缘干细胞移植术疗效对比观察  

Observation and analysis the efficacy ofpterygium excision surgery with phototherapeutic keratectomy and corneal limbal stem cells autograft transplantation

作　　者：张亚娟[1] 孙兰萍[1] 刘桂芬[1] 任延军[1] 李冀[1] 郝俊华[1] 庞琳[1] 刘霞[1] 王娟[1] 

机构地区：[1]河北邯郸市眼科医院眼科,邯郸056001

出　　处：《中国实用眼科杂志》2011年第3期272-274,共3页Chinese Journal of Practical Ophthalmology

摘　　要：目的对比观察两种治疗翼状胬肉的手术效果。方法翼状胬肉患者123例124只眼，随机分为A组，（60只眼），行翼状胬肉切除联合准分子激光治疗性角膜切削术（PTK）；B组，（64只眼），行翼状胬肉切除联合自体角膜缘干细胞移植术。比较其复发率、术后角膜修复『青况、手术前后泪膜恢复及散光和矫正视力提高情况。结果术后复发率两组差异无统计学意义，A组患者术后早期角膜修复情况、泪膜破裂时间的提高优于B组（P〈0．01）。矫正视力的提高及散光减少在早期二者差异无统计学意义，晚期A组略高于B组（P〈0．05）。结论单纯胬肉切除联合准分子激光治疗性角膜切削术优于胬肉切除联合自体角膜缘干细胞移植术。Objective To explore a safe and simple method ofpterygium surgery to reduce recurrence rate and side effect. Methods AII 123 patients （124 eyes） were randomly divided into two groups： PTK surgery group （group A, 60 eyes） and corneal limbal stem cells autograft transplantation surgery group （group B, 64 eyes）, then compared the recurrence rate, satisfaction rate, reparation of cornea, and tear function, astigmatism, beast corrected visual acuity （BCVA） before and after surgery. Results The recurrence rate of two groups was similar. There were statistically significant different of the reparation of cornea and tear function （BUT） after surgery in early days, P 〈0.001. No significant difference was found in eyesight raise and astigmatism decrease in early stage, but in later stage group A were raised compared group B, P 〈0.05. Conclusions Pterygium excision surgery with phototherapeutic keratectomy is a method which can achieve good effect and decrease surgery complication maximality.

关 键 词：翼状胬肉 手术切除 准分子激光治疗性角膜切削术 自体角膜缘干细胞移植术 

分 类 号：R772.2[医药卫生—眼科]