年轻子宫内膜癌的临床特点及预后分析  

Analysis of clinical characteristics and prognosis of young patients with endometrial cancer

作　　者：邹晓琴[1] 李从铸[1] 黄恬[1] 吴京[1] 李丹妍[1] 

机构地区：[1]汕头大学医学院第二附属医院妇产科,515000

出　　处：《中国医师进修杂志》2011年第9期15-17,共3页Chinese Journal of Postgraduates of Medicine

摘　　要：目的探讨年轻子宫内膜癌的临床特点及预后。方法对82例确诊的子宫内膜癌患者进行回顾性分析，其中≤45岁31例（年轻组），〉45岁51例（年老组），分析两组患者的临床特点、诊治情况及预后。结果年轻组原发性不孕率和妊娠〈3次率[38．7％（12／31）和74．2％（23／31）]明显高于年老组[3．9％（2／51）和29．4％（15／51）]（P〈0．05）。两组患者肌层浸润程度比较，差异有统计学意义（P〈0．05）；而病理类型、组织学分级、手术病理分期、5年生存率及复发时间比较，差异均无统计学意义（p〉0．05）。结论不孕或少孕为年轻子宫内膜癌的发病因素；年轻子宫内膜癌肌层浸润程度较年老患者轻，病理类型、组织学分级、手术病理分期与年老患者相似，但并没有获得比年老者更好的预后。Objective To investigate the clinical characteristics and prognosis of young patients with endometrial cancer. Methods Eighty-two cases with endometrial cancer were analyzed retrospectively, 31 cases in the young group were ~〈 45 years old, and 51 cases in the old group were 〉 45 years old. The clinical characteristics, diagnosis, treatment and prognosis between the two groups were compared. Results Twelve cases with primary infertility took up 38.7% in the young group,23 cases with less than 3 times of pregnancy occupied 74.2%, and there was no statistical difference, compared with the old group [ 3.9%（2/51 ） and 29.4% （15/51）] （P 〈 0.05）. There was statistically significant between the two groups in myometrial invasion （P 〈 0.05 ）;while there was no significance between the two groups in pathological type, histological grade, clinical stage, 5-year survival rate and recurrence period （P 〉 0.05 ）. Conclusion Infertility or less pregnancy are risk factors for endometrial cancer in the young; the degree of endometrial invasion in the young is more shallow than that in the old; there is no significant difference between the young and the old in pathological type, histological grade and clinical stage; but the prognosis is similar between the young and the old patients.

关 键 词：子宫内膜肿瘤 预后 年轻 

分 类 号：R737.33[医药卫生—肿瘤]