巩膜瓣下蓄水池样小梁切除术联合羊膜植入、丝裂霉素C治疗难治性青光眼  

Clinical analysis of trabeculectomy with sluice pool like filtrating under scleral flap combined with amniotic membrane transplantation and mitomycin-C in treating refractory glaucoma

作　　者：刘伟 李茜 任晓冬 田春玲 魏玉斌 乔玉春 王建亮 

机构地区：[1]张家口市第四医院,河北075000

出　　处：《中华眼外伤职业眼病杂志》2011年第1期53-56,共4页Chinese Journal of Ocular Trauma and Occupational Eye Disease

摘　　要：目的探讨难治性青光眼应用巩膜瓣下蓄水池样小梁切除术联合羊膜植入及应用丝裂霉素C治疗的临床疗效。方法83例（102眼）难治性青光眼进行瓣下蓄水池样小梁切除术，同时联合应用丝裂霉素C、羊膜植入和可拆除调整缝线。术后随访4～28个月，平均15个月。结果视力：有7眼视力较术前提高，90眼视力无变化，5眼视力下降（P〉0．05）。眼压：术前（34．48±6．35）mMHg，术后（14．23±4．57）mmHg（P〈0．01）。滤过泡：全部病例出现功能性滤过泡95眼，非功能性滤过泡7眼。结论瓣下蓄水池样小梁切除术联合羊膜植入、丝裂霉素C、可拆除调整缝线治疗难治性青光眼能有效降低眼压，进而保护视功能。Objective To investigate the clinical efffect of compound trabeculectomy with sluice pool like filtrating under scleral flap combined with amniotic membrane transplantation and mitomyein-C in treating refractory glaucoma. Methods 102 eyes of 83 refractory glaucoma patients were treated with compound trabeeuleetomy with sluice pool like filtrating under scleral flap, and conbined with mitomyein-C, adjustable stitches, and amniotic membrane transplantation. Results During an average follow up of 15 months （4 months to 28 months）. The vision improved 7 eyes, remained the same in 90 eyes, worse than before in 5 eyes, whose differences were not notable （ P 〉 0. 05 ）. The preoperative intraoeular pressure （lOP） was 34. 48 ± 6. 35 mmHg, and the postoperative IOP was 14. 23 ± 4. 57 mmHg （P 〈 0. 01 ）. Functional filtrating bleb formed in 95 eyes and nonfunctional one in 7 eyes. Conclusion Trabeeuleetomy with sluice pool like filtrating under scleral flap combined with amniotie membrance transplantation, adjustable stitches and mitomyein-C in treating refractory glaucoma can effectively decrease the intraoeular pressure and keep visual funtion.

关 键 词：青光眼 难治性 瓣下蓄水池 羊膜植入 丝裂霉素C 可拆除调整缝线 小梁切除术复合式 

分 类 号：R779.6[医药卫生—眼科]