青稞提取物对高脂血症人群降血脂功能研究  

Effect of Extracts of Barley on Lowering Serum Lipid in Hyperlipidemia Population

作　　者：陈东方[1] 张聪恪[1] 李立[1] 王海玉[1] 张焱[1] 

机构地区：[1]河南省疾病预防控制中心毒理室,河南郑州450016

出　　处：《实用预防医学》2011年第3期525-527,共3页Practical Preventive Medicine

摘　　要：目的探讨青稞提取物对高脂血症人群辅助降血脂作用。方法将106例高脂血症者按血脂水平随机分为受试组和对照组,受试组连续服用受试物45 d。服用前后测定血清中总胆固醇(TC)、甘油三酯(TG)和高密度脂蛋白胆固醇(HDL-C)水平和安全性指标。结果试食后受试组TC水平明显下降,下降率为10.64%,自身前后比较及与对照组比较差异有统计学意义(P<0.01);TG水平明显下降,下降率为16.65%,自身前后比较及与对照组比较差异有统计学意义(P<0.05);HDL-C水平升高0.11 mmol/L,与对照组比较差异无统计学意义(P>0.05)。各项安全性指标试验前后均无明显改变。结论青稞提取物对高脂血症人群具有辅助降血脂作用。Objective To explore the effect of extracts of barley on lowering serum lipid in hyperlipidemia population. Methods Totally 106 hyperlipidemia volunteers were randomly divided into test group and control group according to contents of serum lipid.The volunteers in test group were orally administered with extracts of barley on 45 successive days.Before and after the test,serum total cholesterol（TC）,triglyceride（TG）,high density lipoprotein cholesterol（HDL-C） and the indexes of safety were determined. Results After the test,the levels of TC and TG in test group decreased significantly,and the decreasing rates of TC and TG were 10.64% and 16.65%,respectively.After the test,there were statistically significant differences in the levels of TC and TG between control group and test group,also between before and after the test in test group.The level of HDL-C was increased by 0.11 mmol/L,and there was no statistically significant difference between test group and control group（P〉0.05）.No significant change was found in all the indexes of safety before and after the test. Conclusions Extracts of barley has serum lipid-lowering effects in hyperlipidemia population.

关 键 词：青稞提取物 高脂血症 降血脂 人体试验 

分 类 号：R459.3[医药卫生—治疗学]