儿童涎腺上皮性肿瘤的临床研究  

Clinical study of salivary gland epithelial tumors in children.

作　　者：张文峰[1] 赵怡芳[1] 郑立武 严全梅[1] 

机构地区：[1]湖北医科大学口腔医学院颌面外科,武汉市430079

出　　处：《口腔医学纵横》1999年第3期141-142,共2页Journal of Comprehensive Stomatology

摘　　要：目的：探讨儿童涎腺上皮性肿瘤的发病特点及诊疗要点。方法：对４５例经病理证实的１６ 岁以下儿童涎腺上皮性肿瘤患者的临床资料进行统计分析。结果：儿童涎腺上皮性肿瘤，男女之比为１．１４：１；发病平均年龄为１０．３４岁，随着年龄的增大，患病比随之增高，但年龄越小患恶性肿瘤的可能性愈大，且恶性程度愈高；发病部位以腮腺、颌下腺及腭部多见，大小涎腺间良恶性肿瘤患病比无明显差别；良性肿瘤以多形性腺瘤常见，恶性肿瘤以粘液表皮样癌最常见。良性肿瘤术后少有复发，恶性肿瘤复发率约占被随访者的５０％ 。结论：对儿童涎腺上皮性肿瘤，尤其是患儿年龄愈小时，患恶性肿瘤的可能性更大，应引起高度警惕。恶性肿瘤手术应彻底，不可因患儿年龄小过分强调保留面神经而增加复发的机会。Objective: To evaluate the clinical characteristics and management approach of pediatric salivary gland epithelial tumors. Methods: 45 pediatric cases(≤15 years) with salivary gland epithelial tumors, which were histopathologically diagnosed, were retorspectively analyzed. Results: In children with gland epithelial tumor. Male∶female ratio was 1.14:1 and the mean onset age was 10.34 years. There was a notable increase of mortality with age growth. The younger the patients, the higher the probability of tumor to be malignant and the more severity of the malignancy. The common occurrence sites of tumor were the parotids, submandibular glands and palate, and there was no significant difference of the prevalence malignant and benign tumors between the major and minor salivary glands. The commonest benign tumor was pleomorphic adenoma, while the commonest malignant tumor was mucoepidermoid carcinoma. Benign tumors had a rare tendency to reoccur while the malignant had a 50% recurrence rate. Conclusions: It should be noticed that gland epithelial tumor in younger children was more likely manifests tendency of malignance. In order to reduce the recurrence rate of malignant tumors, surgeons should employ aggressive approach and need not pay much attention to the integrity of facial nerve in the malignant tumors.

关 键 词：上皮性肿瘤 儿童 涎腺肿瘤 临床研究 

分 类 号：R739.87[医药卫生—肿瘤]