环核苷酸在正常大鼠神阙、肾俞穴位组织内的分布及针刺后的变化  

The Distribution of Cyclic Nucleoside in Points Shenque (RN8) and Shenshu (B23) Tissues of Normal Rats and the Changes After Acupuncture

作　　者：曲丽芳[1] 宫斌[1] 张再良[1] 叶进[1] 汪泳涛[1] 

机构地区：[1]上海中医药大学

出　　处：《上海针灸杂志》1999年第4期36-37,共2页Shanghai Journal of Acupuncture and Moxibustion

摘　　要：探讨环核苷酸在不同穴位的分布及与针刺效应的关系。方法运用放射免疫测定技术对神阙、肾俞穴位组织内环磷酸腺苷（ｃＡＭＰ）、环磷酸鸟苷（ｃＧＭＰ）进行了测定。结果正常大鼠神阙穴位组织内的ｃＡＭＰ、ｃＧＭＰ明显高于肾俞穴（Ｐ＜０．００１，Ｐ＜０．０５），电针肾俞穴时，两穴位ｃＧＭＰ的差异消失。结论提示环核苷酸在不同穴位的差异性分布及对针刺的特异性反应，可能是不同穴位具有不同的特异性功能的物质基础之一。Objective To investigate the distribution of cyclic nucleoside in different points and its relation with acupuncture effect. Method Radioimmunoassay was used to measure cAMP and cGMP in points Shenque (RN 8) and Shenshu (BL 23) tissues. Results In normal rats,cAMP and cGMP were significantly higher in point Shenque than in point Shenshu tissue (P<0.001,P<0.05); the difference in cGMP between the two groups disappeared during electropuncture of point Shenshu. Conclusion It is suggested that the different distribution of cyclic nucleoside in different points may be one of the substance bases for the different specific function that different points perfourm.

关 键 词：AMP GMP 神阙穴 肾俞穴 针刺效应 环核苷酸 

分 类 号：R245[医药卫生—针灸推拿学] Q524[医药卫生—中医临床基础]