红车轴草化学成分研究  

Studies on the chemical constituents of Trifolium Pratense L.

作　　者：王少滕[1] 曾小英[2] 高洁[2] 宋发军[2] 

机构地区：[1]中南民族大学药学院,武汉430074 [2]中南民族大学生命科学学院,武汉430074

出　　处：《华中师范大学学报（自然科学版）》2011年第1期72-74,94,共4页Journal of Central China Normal University：Natural Sciences

基　　金：中央高校科研基本业务费专项资金重点项目(CZZ1000003)

摘　　要：运用正相、反相硅胶柱层析和HPLC对红车轴草(Trifolium Pratense L.)的化学成分进行研究,并利用现代波谱技术鉴定化合物的结构.从红车轴草全草的乙醇提取物中分离得到5个化合物(图1),分别鉴定为豆甾-4-烯-3-酮(1),豆甾-4-烯-3,6-二酮(2)和α-豆甾-4-烯-3,6-二酮(3),齐墩果烯酯(4)和1-羟基-5,6,7-三甲氧基双苯吡酮(5),所有化合物均为首次从该植物中分得.To study the chemical constituents of Trifolium Pratense L. , the chemical constituents were isolated and purified by normal and reverse column chromatography and HPLC. Their structures were identified by spectral analysis respectively. Five com- pounds were isolated from the EtOH extract of Trifolium Pratense L. They were iden- tified as stigmast 4-en-3-one （ 1 ）, stigmast-4-en-3,6-dione （ 2）, a-stigmast-4-en-3,6-dione （3）, 12-en-3-one-methyl-oleanolicate （ 4 ）, 1-hydroxy-5,6,7-thrimethoxy-xanthone （ 5 ）. All compounds were isolated from the plant for the first time.

关 键 词：红车轴草 化学成分 甾体化合物 三萜化合物 

分 类 号：O629.2[理学—有机化学]