胰腺实性假乳头状瘤的临床病理特征  

The Clinicopathological Features of Solid-Pseudopapillary Tumor of Pancreas

作　　者：娄欣[1] 张全武[1] 肖艳景[1] 赵红梅[1] 和莹莹[1] 

机构地区：[1]郑州市中心医院病理科,河南郑州450007

出　　处：《肿瘤基础与临床》2011年第1期50-51,共2页journal of basic and clinical oncology

摘　　要：目的探讨胰腺实性假乳头状瘤的临床病理特征。方法回顾性分析3例胰腺实性假乳头状瘤的临床资料、组织病理和免疫表型,并复习相关文献。结果胰腺实性假乳头状瘤多见于女性,可发生于胰腺的任何部位,肿瘤呈囊实性,细胞形态一致,核分裂相罕见,瘤细胞形成特征性假乳头结构。免疫组化结果显示:Vim(+)、CD56(+)、CD10(+)、CK(-)、CgA(-)。结论胰腺实性假乳头状瘤是一种罕见的肿瘤,具有多种组织学结构、细胞形态及多向分化的免疫组化表型;该肿瘤发展缓慢,生存时间长,但少数可复发、转移,为低度恶性肿瘤。Objective To explore the clinicopathologic features of solid-pseudopapillary tumors of pancreas （SPTP）. Methods The clinical data, histopathological features and immunophenotypes of three patients with SPTP were observed retrospectively, and the pertinent literatures were reviewed. Results The SPTP was more common in the female patients, and could occur in any part of the pancreas. The tumors were solid-cystid, the tumor cells were uniform, the mitotic figures were rarely seen, and the tumor cells were arranged with typical false nipple con- struction. The tumor cells were positive for Vim,CD56 and CD10; while CK, CgA were all negative. Conclusion The SPTP is rare tumors with nmhiple histopathological features, cell forms and immunophenotypes. The tumor growth is slow, and the survival time is long. But small number of tumors are low-grade malignant, and can relapse or metastasize.

关 键 词：胰腺 实性假乳头状瘤 临床病理特征 免疫组化 

分 类 号：R734.2[医药卫生—肿瘤]