膳食钠盐、体质量指数与良性前列腺增生关系的研究  

Association of dietary sodium intake,body mass index with clinical benign prostatic hyperplasia

作　　者：张黎月[1] 文娟[1] 齐建军[1] 卢智泉[1] 

机构地区：[1]辽宁医学院预防医学教研室,辽宁锦州121001

出　　处：《重庆医学》2011年第11期1065-1067,共3页Chongqing medicine

基　　金：辽宁省教育厅科学技术研究基金资助项目(2008424)

摘　　要：目的 探讨老年男性膳食钠盐、体质量指数（BMI）与良性前列腺增生（BPH）危险性之间的关系.方法 采取以医院为基础的病例对照研究.研究组由经组织学检查证实患BPH的男性患者组成,对照组由因患其他疾病入住与研究组患者相同医院的同期患者组成.研究组与对照组各360例,1∶1匹配.采用标准调查表对全部研究对象进行问卷调查,同时对身高和体质量进行测量.采用食物频率调查表（FFQ）,调查研究对象的膳食情况.采用多元logistic回归模型对患者膳食钠盐、BMI与BPH的比值比（OR）及其相应的95%可信区间（CI）进行估计.结果 研究组患者钠盐摄入量[（15.39±3.17）g/d]明显高于对照组[（14.67±3.07）g/d],55～59岁年龄组中,研究组与对照组患者钠盐摄入量最高.65岁之后,随着年龄的增加,研究组患者钠盐摄入量明显高于对照组.调整了年龄及热能的摄入量后,钠盐总摄入量与BPH呈正相关（χ2=12.095,P=0.007）.并且随着钠盐摄入量的增加,发生BPH的危险性明显升高.与钠盐摄入量最低的对照组比较,研究组钠盐摄入量最高者的OR值显著增加（OR=1.827,95%CI：1.206～2.769,P=0.004）.结论 钠盐摄入量与BPH呈正相关,高钠膳食可能是BPH的一个危险因素.Objective To examine the association between dietary sodium intake,body mass index（BMI）and clinical benign prostatic hyperplasia（BPH）risk in older men. Methods A hospital-based case control study was conducted. Cases（n 360）were men with histologically confirmed BPH, and controls （n = 360）were men,admitted to hospital for many different diseases which not related with prostatic conditions. Case and control were matched with 1 ： 1. Using a standardized structured questionnaire, all subjects were interviewed to measure body height and weight. Data on diet were obtained via a food frequency questionnaire. The odds ratios （OR）and 95% confidence intervals（CI）of BPH for dietary sodium intake and BMI were estimated using unconditional muhiple lo gistic regression models. Results Dietary sodium intake（15.39±3.17）g/d in cases was obviously more than the controls（14.67±3.07）g/d. Dietary sodium was the highest among 55 to 59 years old. Compared to the controls,dietary sodium intake was higher in cases,with increase of the cases＇ age. After adjusted for energy,dietary sodium intake was positively related to clinical BPH （X^2= 12. 095,P=0. 007）. The odds of BPH significantly increased with increasing dietary sodium intake. Men in the highest quartile of dietary sodium intakes were nearly twice as likely to report BPH （OR= 1. 827,95% CI = 1. 206 - 2. 769, P = 0. 004）. Conclusion Dietary sodium intake is positively associate with BPH. A high intake of dietary sodium might be a risk factor of clinical BPH.

关 键 词：前列腺增生 钠 膳食 人体质量指数 

分 类 号：R697.3[医药卫生—泌尿科学]