治疗恶性胸腔积液在心包腔积液三种方法比较  

The expression of insulin like growth factor II mRNA in rat polycystic ovary

作　　者：卞慧敏 钱本烨 

机构地区：天津市胸科医院胸内科

出　　处：《医师进修杂志》1999年第9期25-26,共2页Journal of Postgraduates of Medicine

摘　　要：目的：寻找治疗恶性胸腔积液在心包腔积液的有效方法。方法：采用向腔内注射四环素、短棒、５－Ｆｕ＋丝裂霉素三种方法各８例治疗恶性胸腔和心包腔积液。结果：四环素与短棒组有效率为８８．８％和８３．３％，两组间没有显著性差异Ｐ〉０．０５，５－Ｆｕ加丝裂且有效率为４４．４％，与短棒组有显著性差异Ｐ〈０．０５，与四环素组有极显著性差异Ｐ〈０．００１。The expression of insulin like growth factor II mRNA in rat polycystic ovary$$$$ ZHU Hui, NI Jiang, XING Zhijun, WU Yanwan Department of Physiology, Harbin Medical University, Harbin 150086 National Research Institute for Family Planning Objective: To study insulin like growth factorII (IGFII) mRNA expression in rat polycystic ovary model. Design: In situ hybridization. Method: In situ hybridization of rat ovary was performed with digoxigenin labeled IGFII cDNA probe. Results: The hybridized signals were distributed in the cytoplasm of thecal cells in polycystic ovary of rat and no signal was observed in the granulose cells. Conclusion: Reduced expression of IGFII mRNA in granulosa cells likely was associated with follicle development defect in rat PCO. Key words: Polycystic ovary Insulinlike growth factorII In situ hybridization

关 键 词：胸腔积液 心包积液 四环素 丝裂霉素 癌性 治疗 

分 类 号：R730.53[医药卫生—肿瘤]