58例骨与软组织恶性肿瘤的介入治疗——临床、影像与病理综合评价  

Interventional therapy of 58 cases with malignant bone and soft tissue tumors: clinical, radiographic and pathological evaluation

作　　者：金龙[1] 邹英华[1] 栗怀广[2] 彭勃[1] 蒋学祥[1] 吕永兴[1] 高玉洁[1] 

机构地区：[1]北京医科大学第一医院医学影像科,100034 [2]北京医科大学第一医院骨科,100034

出　　处：《中华放射学杂志》1999年第9期629-632,共4页Chinese Journal of Radiology

摘　　要：目的　通过对 5 8例骨与软组织肿瘤局部动脉内行灌注化学药物治疗 (简称化疗 )和栓塞术后的临床、放射学变化及手术病理研究 ,探讨骨与软组织肿瘤介入治疗的技术和疗效及血管造影表现在评价疗效方面的意义。方法　 5 8例骨与软组织肿瘤患者接受介入治疗 ,治疗后随访 3～ 2 4个月 ,观察临床及放射学改善情况 ,计算肿瘤坏死百分比并与血管造影表现对照。结果　治疗后大部分患者临床指标明显改善 ,肢体肿瘤患者 92 %行保肢手术 ,术后局部复发率为 13 .6%。手术病理示5 3 % ( 10 / 19)的患者肿瘤坏死率达 90 %以上 ,术后血管造影表现与病理结果相符。结论　介入治疗是骨与软组织肿瘤治疗的有效方法 ,血管造影是判断疗效及预后的可靠指标。Objective To assess the value of transarterial infusion chemotherapy and embolization in the treatment of malignant bone and soft tissue tumors Methods 58 cases of malignant bone and soft tissue tumors were included in this group The clinical and radiographic improvement were observed and correlated with pathological findings Results Marked improvement of the symptoms in most patients was noticed Limb sparing resection was obtained in 92% patients and the local recurrence rate was 13 6% Tumor necrosis of 90%-100% was revealed by pathology in 53%(10/19) patients Significant correlation between angiographic and pathological findings was presented Conclusions Interventional therapy is a safe and effective procedure in treating malignant bone and soft tissue tumors Follow up angiographic findings can predict the respones of the patients

关 键 词：骨肿瘤 软组织肿瘤 介入放射学 

分 类 号：R738.105[医药卫生—肿瘤] R738.605[医药卫生—临床医学]