缺血性结肠炎诊断的多因素分析  

Multivariate Analysis in Diagnosis of Ischemic Colitis

作　　者：崔海宏[1] 王滨[1] 赵佳[1] 李爱民[1] 刘丽丽[1] 魏伟[1] 

机构地区：[1]解放军第456医院消化内科

出　　处：《胃肠病学》2010年第12期732-734,共3页Chinese Journal of Gastroenterology

摘　　要：背景：缺血性结肠炎是由于肠道血液供应不足或回流受阻致结肠壁缺氧损伤所引起的急性或慢性炎症性病变,其发病率近年呈增高的趋势.目的：研究缺血性结肠炎的危险因素,为其诊断提供参考.方法：回顾性分析36例缺血性结肠炎患者和39例对照者,对可能导致缺血性结肠炎的相关因素行单因素分析和Logistic回归分析.结果：单因素分析显示年龄、病程、基础疾病、便秘和肠易激综合征与缺血性结肠炎有关.Logistic回归分析进一步确定病程、基础疾病以及便秘为缺血性结肠炎的危险因素,OR值分别为3.519、6.880和4.467.结论：缺血性结肠炎的发生与患者有无基础疾病以及便秘密切相关,这可能是导致血管和肠管改变的重要因素.此外,病程亦有助于诊断缺血性结肠炎.Background: Ischemic colitis is the acute or chronic inflammation caused by hypoxic damage of colon wall because of inadequate blood supply or obstruction of venous return.The incidence of this disease tends to increase in recent years. Aims: To study the risk factors of ischemic colitis,so as to provide evidences for its diagnosis.Methods: Thirty-six cases of ischemic colitis and 39 control cases were analyzed retrospectively.Single factor analysis and Logistic regression analysis were performed to analyze the related factors that might result in ischemic colitis.Results: Single factor analysis showed that age,course of disease,underlying disease,constipation and irritable bowel syndrome were correlated with ischemic colitis.Logistic regression analysis showed that course of disease,underlying disease and constipation were the risk factors of ischemic colitis,OR were 3.519,6.880 and 4.467,respectively.Conclusions: Underlying disease and constipation are closely correlated with ischemic colitis,which may be the important factors leading to vascular and intestinal wall changes.In addition,course of disease also contributes to the diagnosis of ischemic colitis.

关 键 词：结肠炎 缺血性 诊断 危险因素 LOGISTIC模型 

分 类 号：R574.62[医药卫生—消化系统]