肿瘤病人服用甲地孕酮配合化疗36例疗效观察  

Cancer patients taking megestrol acetate combined with chemotherapy in 36 cases

作　　者：傅饶[1] 钟佳洋[1] 

机构地区：[1]四川省肿瘤医院,四川成都610041

出　　处：《中国中医药咨讯》2011年第9期3-4,共2页

摘　　要：目的观察肿甲地孕酮分散片辅助止吐30例疗效观察。方法将36例化疗晚期肿瘤患者随机分成对照组和观察组各18例。对照组单用化疗；治疗组化疗加甲地孕酮。化疗前1天开始服用甲地孕酮160mg，1次，天直至化疗结束后7天；对照组单用化疗，2个周期化疗后观察两组患者化疗后胃肠道反应、食欲、体重、骨髓抑制情况、karnofsky评分情况。结果经2个周期化疗后，观察组在胃肠道反应、食欲、体重、karnofsky评分方面均有明显改善。1例出现血糖升高，1例双下肢水肿，经对症处理症状均消失。结论甲地孕酮毒副反应轻，对化疗期间改善患者的生活质量、减少化疗毒副反应有明显帮助，值得临床推广运用。Objective To observe the swelling of megestrol acetate＇tablet auxiliary antiemetic 30 cases. Methods 36 patients with chemotherapy for advanced cancer were randomly divided into control group and observation group of 18 cases. Control group, chemotherapy alone; chemotherapy treatment group megestrol. 1 day before chemotherapy began taking megestrol acetate 160 rag, 1 times / day until 7 days after chemotherapy; control group, chemotherapy alone, two cycles of chemotherapy after chemotherapy were observed after gastrointestinal reactions, loss of appetite, weight, bone marrow inhibition, karnofsky score situation. Results After 2 cycles of chemotherapy, the observation group in the gastrointestinal tract reactions, loss of appetite, weight, karnofsky scores were significantly improved terms. 1 patient had elevated blood sugar, and 1 lower extremity edema, symptoms disappeared after symptomatic treatment. Conclusion The toxicity of Megestrol light on the life of patients during chemotherapy improve quality and reduce the toxicity of chemotherapy has significantly helped, is worthy of clinical use.

关 键 词：化疗 辅助止吐 甲地孕酮 疗效观察 

分 类 号：R730.53[医药卫生—肿瘤]