多发性骨髓瘤合并侵袭性肺真菌感染22例临床分析  

Clinical Analysis of 22 Cases of Multiple Myeloma with Invasive Pulmonary Fungal Infection

作　　者：谢瑜[1] 谭琳[1] 吴迪[2] 

机构地区：[1]昆明医学院第一附属医院血液科,昆明650032 [2]昆明医学院第一附属医院骨科,昆明650032

出　　处：《中国医药导刊》2011年第2期236-237,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨临床医生对多发性骨髓瘤合并侵袭性肺真菌感染的认识,改进治疗措施,减少侵袭性肺真菌感染率、死亡率。方法:分析住院的多发性骨髓瘤合并肺侵袭性真菌感染患者22例的一般临床资料、微生物学检查及治疗情况。结果:侵袭性肺真菌感染的发病率不断增高,病原菌以白色念球菌为主,22例患者应用抗真菌药物后总有效率为68.2%,死亡率为22.7%。结论:侵袭性肺真菌感染是多发性骨髓瘤患者化疗期间严重的并发症和主要的死亡原因之一。Objective： To improve the comprehension of motivation of multiple myeloma accompanied with invasive pulmonary fungal infection, to improve therapeutic measure, reduce fungal infection, mortality rate. Methods：Retrospective study of the fungous infection table,microbiology, treatment and outcome of 22 cases who had be clearly diagnosed as multiple myeloma accompanied invasive pulmonary fungal infectionl .Resnlts：Invasive puhnonary fimgal infections continued to increase in the incidence, the most commen fungus was Candida, 22 patients after application of antifungal agents had a total efficiency of 68.2%, mortality rate was 22.7%.Conclusions：Invasive pulmonary fungal infections in patients with multiple myeloma during chemotherapy are important complications and the mainly cause of death.

关 键 词：多发性骨髓瘤 真菌 肺 

分 类 号：R733.3[医药卫生—肿瘤]