维C银翘片挥发性成分GC-MS特征图谱研究  

Study on GC-MS specific chromatogram of volatile oil from Wei C Yinqiao tablets

作　　者：黄华花[1] 吴春敏[1] 

机构地区：[1]福建省药品检验所,福州350001

出　　处：《药物分析杂志》2011年第4期768-771,共4页Chinese Journal of Pharmaceutical Analysis

摘　　要：目的:建立维C银翘片挥发性成分GC-MS特征图谱。方法:采用HP-FFAP石英毛细管柱(30.0 m×25 mm×0.32μm),氦气为载气,60～230℃程序升温;质谱检测器,扫描范围(m/z)40～600。结果:分析了5个企业生产的维C银翘片挥发性成分,建立了维C银翘片挥发性成分GC-MS特征图谱,并确定了30个峰,其中乙酸、薄荷酮、薄荷脑、松油烯-4-醇、胡薄荷酮、α-松油醇为6个主要共有峰。结论:本方法简单、准确,为制定维C银翘片的质量标准提供了有效的方法。Objective：To establish the GC-MS specific chromatogram of volatile oil from Wei C Yinqiao tablet.Methods： The samples were analyzed on HP-FFAP column（30.0 m×25 mm×0.32 μm） with programming temperature from 60 ℃ to 230 ℃.Helium was used as carrier gas.MS monitoring mode was used to scan the ions of m/z from 40 to 600.Results：Thirty peaks were found in the GC-MS specific chromatogram of volatile oil from Wei C Yinqiao tablet,including six main common peaks：Acetic Acid,Menthone,Menthol,terpinenol-4-ol,Pulegone and alpha-terpineol.Condusion：The method is simple,accurate,and can be used as a quality control method for Wei C Yinqiao tablet.

关 键 词：维C银翘片 挥发性成分 GC-MS 特征图谱 

分 类 号：R917[医药卫生—药物分析学]