多层螺旋CT灌注成像对原发性肝癌的评价  

Evaluation of multi-slice CT perfusion imaging in hepatocellular carcinoma

作　　者：燕平[1] 

机构地区：[1]湖北医药学院附属太和医院肿瘤科,湖北十堰442000

出　　处：《西部医学》2011年第4期643-645,共3页Medical Journal of West China

摘　　要：目的探讨多层螺旋CT灌注成像在原发性肝癌中的价值。方法对25例原发性肝癌进行多层螺旋CT灌注成像,动态电影模式扫描,所有数据经工作站软件处理并计算组织血流量(blood flow,BF)、血容量(blood volume,BV)、平均通过时间(mean transittime,MTT)、毛细血管通透性(permeability surface,PS)、肝动脉供血分数(hepatic arterial fraction,HAF),比较肿瘤组织、瘤旁组织及正常肝组织各灌注参数的变化。结果肝癌组织BF、HAF明显高于瘤旁组织及正常肝组织,而MTT明显降低,且具有显著性差异;BV和PS值与正常组织无显著差异。结论肝癌CT灌注参数(BF、HAF和MTT)可有效的评价原发性肝癌的血流动力学改变,具有重要临床价值。Objective To evaluate the application value of multislice CT perfusion imaging in hepatocellular carcinoma（HCC）.MethodsPerfusion scans were performed with 16-slice CT in 25 patients with HCC.Contrast medium-enhanced dynamic CT was performed with a statictable position for 50 seconds,and the data were analyzed with software to calculate tissue blood flow（BF）,blood volume（BV）,mean transittime（MTT）,permeability surface（PS）,and hepatic arterial fraction（HAF）.Perfusion parameters of tumor,the periphery of tumor and normal liver were compared.Results HCC showed high BF,HAF,HAP and short MTT compared with those of the periphery of HCC and normal liver.ConclusionThe changes of hepatic perfusion parameters（BF,HAF and MTT） have great valueon evaluating the hemodynamics of HCC.

关 键 词：肝癌 灌注成像 体层摄影术 X线计算机 

分 类 号：R735.7[医药卫生—肿瘤] R814.42[医药卫生—临床医学]