陀螺刀治疗脑膜瘤临床分析  

Clinical analysis of patients with meningiomas treated by top knife

作　　者：顾冲[1] 王建忠[1] 刘坤[1] 谷凌云[1] 

机构地区：[1]江苏省淮安市第三人民医院神经外科,223001

出　　处：《中国现代医药杂志》2011年第4期41-43,共3页Modern Medicine Journal of China

摘　　要：目的探讨陀螺旋转式钴60立体定向放射治疗系统(陀螺刀)治疗脑膜瘤的方法和疗效。方法 应用上海伽玛星科技发展有限公司的GMXB型陀螺旋转式钴60立体定向放射治疗系统,治疗26例脑膜瘤患者,肿瘤直径1.1～5.5cm,多靶点联合照射,50%～60%等剂量曲线包绕,处方剂量周边3600～5000cGy,中心9600～11700cGy,单次剂量300～470cGy,1次/日,5次/周,一个疗程7～11次。结果随访3～18个月,按实体瘤疗效WHO评价标准,完全缓解(CR)3例,占11.54%,部分缓解(PR)12例,占46.15%,稳定(SD)9例,占34.62%,进展(PD)2例,占7.69%。肿瘤控制率92.31%,症状改善率84.62%。结论陀螺刀治疗脑膜瘤安全、有效,副作用少。Objective To explore the strategy and efficacy of meningiomas treated by top revolves cobalt 60 stereo orientation surgical radiotherapy system. Methods 26 patients with meningiomas were treated by GMB-X type to spiral and cobalt 60 stereo orientation radiotherapy treatment system from Shanghai gamma star compation. Joint multi-target irradiation,tumor diameter 1.1～5.5cm.The duration of treatment was 7～11 times,once a day, five time for a week,each dosage was 300～470cGy,center dosage was 9 600～11 700cGy,and 50%～60% isodose curve surrounded. Peripheral dose was 3 600cGy^5 000cGy. Results All patients were followed-up 3~18 months. Evaluation of solid tumors by WHO criteria, 3 cases（11.54%） of the tumor disappeared, the volume of tumor reduced in 12 cases （46.15%）, 9 cases（34.62%） of the unchanged, 2 cases （7.69%） diabetes insipidus, growth control rate of tumor was 92.31%,clinical symptoms 84.62% were improved. Conclusion Top knife treat meningiomas is safe, effective and less side effects.

关 键 词：脑膜瘤 放射治疗 陀螺刀立体定向放射治疗系统 

分 类 号：R739.45[医药卫生—肿瘤]