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作 者:李靖[1,2] 李鸣皋[2] 吕晓宁[2] 孙海文[2] 马贵喜[2] 刘玉[2] 蒙果[2]
机构地区:[1]军医进修学院研究生队,北京100853 [2]海军总医院全军航海航空医学中心,北京100048
出 处:《军医进修学院学报》2011年第5期506-508,共3页Academic Journal of Pla Postgraduate Medical School
摘 要:目的评价复合碳纤维远红外线装置的复温效果及生物学效应。方法将30只健康新西兰兔随机分为3组,每组10只。各组实验兔经(21.0±0.5)℃人工模拟海水浸泡至肛温30℃,分别采用自然、水浴、复合碳纤维远红外线三种方法进行复温至肛温35℃,记录各组所用复温时间以及复温后体温下降度数,分别在浸泡前、复温前及复温3h后静脉采血,测定红细胞膜ATP酶及血浆乳酸含量。结果水浴组和远红外线组复温均明显快于自然组(P<0.01);远红外线组体温后降幅度最小,水浴组次之,自然组最大(P<0.01);远红外线组复温3h红细胞膜ATP酶活性明显高于水浴组和自然组(P<0.01),血浆乳酸含量明显低于水浴组和自然组(P<0.01)。结论复合碳纤维电热装置救治海水浸泡性体温过低兔,复温速度快、体温后降幅度小;能增加红细胞膜ATP酶含量并降低血浆乳酸含量,有明显的保护性生物学效应。Objective To assess the re-warming and biological effect of far-infrared composite carbon fiber device on hypothermia.Methods Thirty healthy New Zealand rabbits were randomly divided into 3 groups(10 in each group).The rabbits were immersed in(21.0±0.5)℃ artificial ice sea water till their rectal temperature reached 30℃,then spontaneously re-warmed using blanket,or in warm bath or with far-infrared composite carbon fiber till their rectal temperature reached 35℃.The re-warming time and body temperature decrease after re-warming were recorded.Venous blood was collected 3h before immersion and re-warming and 3h after re-warming to measure the levels of ATPase and lactate in RBC membrane and plasma,respectively.Results The re-warming was significantly faster in water bath group and far-infrared group(P0.01).The decreased amplitude of body temperature was the smallest in far-infrared group,followed by water bath group and spontaneous re-warming group(P0.01).The ATPase level in RBC membrane was significantly higher in far-infrared group than in water bath and spontaneous re-warming groups(P0.01).The lactate level in plasma was significantly lower in far-infrared group than in water bath and spontaneous re-warming groups(P0.01).Conclusion Far-infrared composite carbon fiber device can rapidly re-warm ice sea water-induced hypothermia of rabbits with a small decreased amplitude of body temperature,an increased level of ATPase and lactate in RBC membrane and in plasma respectively after re-warming,and a significant protective biological effect.
分 类 号:R83[医药卫生—航空、航天与航海医学]
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