卵巢癌肠道转移手术的可行性分析  

Feasibility Analysis of Surgical Intervention of Intestinal Metastases Originated from Ovarian Cancer

作　　者：徐婉[1] 王晶[1] 王树鹤[1] 尚丽新[1] 

机构地区：[1]北京军区总医院妇产科,北京100700

出　　处：《中国现代手术学杂志》2010年第6期463-465,共3页Chinese Journal of Modern Operative Surgery

摘　　要：目的分析卵巢癌肠道转移手术的可行性及其与预后的关系。方法卵巢癌肠道转移病人35例,行肿瘤细胞减灭术及肠道手术,肠道手术包括肠段切除术15例,肿瘤剥除术20例,术后予规范化疗。结果术后并发症7例,其中肠段切除组发生腹膜炎2例、肠瘘1例、切口感染1例,肿瘤剥除组发生不全性肠梗阻2例、切口感染1例。所有病人随访24个月以上,1,3,5年生存率分别为82.9%、54.3%和34.3%。肠段切除组5年生存率高于肿瘤剥除组(53.3%VS 20.0%,P<0.05);随访2年及5年以上,其缓解率分别为66.7%和26.7%,均高于肿瘤剥除组的5%和0(P<0.05)。结论晚期卵巢癌易转移至肠道,应尽量手术切除受累肠段,术后辅以规范化疗,以提高卵巢癌患者的预后。Objective To analyze the feasibility of surgical intervention and to evaluate the relationship between procedure and prognosis in treatment of intestinal metastases originated from advanced ovarian cancer.Methods 35 women with intestinal metastases originated from ovarian cancer were reviewed.All patients were performed cytoreduction and intestinal surgery,including local intestinal resection in 15（resection group） and tumor stripping surgery in 20（stripping group）.Regular chemotherapy was administrated after the operation.Results Postoperative complications were as follows： 2 of peritonitis,1 of intestinal fistula and 1 of incision infection in resection group,2 of incomplete intestinal obstruction and 1 of incision infection in stripping group.All patients were followed up more than 24 months.The 1,3,5-year survival rate was 82.9%,54.3% and 34.3%.The 5-year survival rate of resection group was obviously higher than that of stripping group（53.3% VS 20.0%,P0.05）.Over 2 or 5 years follow-up,the regression rate was 66.7% and 26.7% respectively in resection group,and both were significantly higher than 5.0% and 0% respectively in stripping group（P0.05）. Conclusions Intestinal tract is the common metastatic site of ovarian cancer.Complete excision of involved intestinal and standard chemotherapy can improve the prognosis of the intestinal metastases of advanced ovarian cancer.

关 键 词：卵巢肿瘤 肿瘤转移 肠 预后 

分 类 号：R737.31[医药卫生—肿瘤]