食管癌相关癌基因的研究进展  

Advances in research of esophageal carcinoma-related oncogenes

作　　者：柏文霞[1] 刘伟[2] 施瑞华[2] 

机构地区：[1]南京医科大学附属江宁医院消化科,江苏省南京市211100 [2]南京医科大学附属第一医院消化科,江苏省南京市210029

出　　处：《世界华人消化杂志》2010年第35期3752-3755,共4页World Chinese Journal of Digestology

摘　　要：食管癌的发生发展涉及多个癌基因改变,本文就几个上调基因:TMEM16A,CTHRC1,整合素α6亚基作简要阐述,为食管癌的早期诊断、预后评估及基因诊治探索可行途径.The development and progression of esophageal carcinoma involve the changes in many oncogenes. In this article,we summarize the roles of some oncogenes,such as TMEM16A,CTHRC1 and integrin a6 subunit,in the development of esophageal carcinoma. Elucidation of the roles of esophageal carcinoma-related oncogenes will be helpful in terms of early diagnosis,evaluation of prognosis and molecular diagnosis of esophageal carcinoma.

关 键 词：食管癌 相关癌基因 跨膜蛋白16A 胶原三股螺旋重复蛋白1 整合素α6亚基 研究 

分 类 号：R735.1[医药卫生—肿瘤]