阿尔茨海默病的危险因素研究进展  

Research progresses on the risk factors of Alzheimer's disease

作　　者：吴一峰[1] 黄河浪[1] 

机构地区：[1]南昌大学公共卫生学院,江西南昌330006

出　　处：《中华疾病控制杂志》2011年第4期336-339,共4页Chinese Journal of Disease Control & Prevention

摘　　要：阿尔茨海默病(alzheimer disease,AD)是一种严重危害老年人健康的慢性退行性疾病,随着人口老龄化的加剧,其发(患)病率有增无减。患病率高、预后差、病因复杂、临床疗效不理想是人们对该病的共同感受,因此消除和减少危险因素已成为研究AD的重要命题。近些年来,人们对AD的病因除了从分子生物学角度进行大量探索,并取得一定成果外,还涉及到社会人口学特征、生物遗传、个人特质与经历、体内某些宏、微量元素含量与分布等因素,并且在该病的预防中越来越被人们关注。本文就目前AD相关的主要危险因素(分子生物学探索除外)研究情况作一概括。Alzheimer disease is a chronic degenerative diseases which has serious harm to the health of elderly people.With the worldwide aging population,AD showed a rising trend in the morbidity.Because of its high prevalence rate,grave prognosis,complex etiology and poor therapeutic effects,the elimination and reduction of risk factors was considered as an important part of AD＇s existing researches.Nowadays,the research about the cause of AD in addition to a large number of evidence from molecular biology,and have made certain achievements,but also involves factors including demographic characteristics,heredity,personal experience and the distribution of chemical element in body,etc.This article focuses on the present AD-related risk factors（no risk factors about molecular biology） and made a brief summary of them.

关 键 词：阿尔茨海默病 危险因素 研究 

分 类 号：R742[医药卫生—神经病学与精神病学] R181[医药卫生—临床医学]