酵母多糖血凝实验检测单疱病毒性角膜炎患者红细胞免疫功能的临床应用  

Clinical application of the zymosan hemagglutination test assay in the detection of the immunological function of the erythrocytes from patients with herpes simplex keratitis

作　　者：程凯灵[1] 茅苏萍[2] 

机构地区：[1]重庆医科大学附属第一医院检验科,400016 [2]重庆医科大学应用技术学院附属医院眼科,400050

出　　处：《重庆医学》2011年第12期1219-1220,1227,共3页Chongqing medicine

摘　　要：目的探讨酵母多糖血凝实验在检测单疱病毒性角膜炎(HSK)患者红细胞免疫功能方面的临床应用价值。方法应用酵母多糖血凝实验检测43例HSK患者(其中活动期15例,非活动期28例)的红细胞免疫功能。并以45例健康献血者为正常对照组。结果 HSK患者红细胞免疫黏附血凝阳性滴度显著低于健康者,差异有统计学意义(P<0.05);而两组补体稀释滴度比较差异无统计学意义。结论酵母多糖血凝实验可以检测HSK患者红细胞免疫功能,HSK患者红细胞免疫功能较健康者明显降低,该实验对HSK患者的疗效判断及愈后评估具有一定的参考价值。Objective To evaluate the clinical application of the zymosan hemagglutination test assay in the detection of the immunological function of the erythrocytes from patients with herpes simplex keratitis（HSK）. Methods The immunological function of the erythrocytes from 43 HSK patients（including 15 cases of active keratitis and 28 of inactive keratitis）were detected by the zymoszan hemaggiutination test,and 45 healthyl blood donors were included as normal controls. Results The positive hemagglutination titers of the immune adherence in HSK patients were significantly lower as compared with those of the healthy controls（P〈0. 0.05）. However,the difference between the complement dilution titers of the two groups were found to be not significant. Conclusion The immunological function of the erythrocytes of the HSK patients can be detected by the zymosan hemagglutination test, which show significantly lower erythorocytic immune function in HSK patients. The zymosan hemagglutinati0n test may provide referential value for the evaluation of the therapeutic effect and prognosis of the patients with HSK.

关 键 词：单纯疱疹病毒属 酵母多糖 红细胞免疫功能 

分 类 号：R772.21[医药卫生—眼科]