Ge-132抑制EB病毒转化人B细胞的研究  

Inhibition of Ge-132 on Transformation of Human B Lymphocytes by Epstein-Barr Virus

作　　者：罗慧玲[1] 李满枝[1] 

机构地区：[1]中山医科大学肿瘤研究所

出　　处：《广东微量元素科学》1999年第8期18-20,共3页Trace Elements Science

摘　　要：研究了试管内无细胞毒性浓度的Ｇｅ－１３２抑制ＥＢ病毒转化人脐血Ｂ淋巴细胞的作用。结果表明，Ｇｅ－１３２（５０～２００ｍｇ／Ｌ）能明显抑制ＥＢ病毒转化人脐血Ｂ淋巴细胞，抑制率为９５１％～４７５４％（Ｐ＜００１）。基于ＥＢ病毒与鼻咽癌密切相关，本结果提示，Ｇｅ－１３２可能有助于鼻咽癌和ＥＢ病毒相关的疾病的预防和治疗。The inhibition of Ge-132 of non-toxic doses on transformation in B lymphocytes from human umbilical cord blood(BL)with Epstein-Barr virus(EBV)in vitro was studied.It was found that transformation effects of BL with EBV was markedly inhibited by Ge-132(50～200 mg/L).The inhibition rates of BL reansformation were 9 51%～47 54%.EBV is associated with napspharyngeal carcinoma(NPC).The results suggest that Ge-132 may help protect against and treat NPC and the diseases associated with EBV.

关 键 词：EB病毒 淋巴细胞转化 锗-132 鼻咽癌 

分 类 号：R739.63[医药卫生—肿瘤]