微波消融术对原发性肝癌肝纤维化指标的影响  

Percutaneous Microwave Coagultion Therapy Influence on Hepatofibrosis of Primary Hepatocellular Carcinoma Serum

作　　者：彭齐荣[1] 肖必[1] 张健[1] 程涛[1] 陈国强[2] 

机构地区：[1]中国人民解放军第458医院全军肝病中心,广州510602 [2]南方医科大学附属珠江医院肿瘤中心

出　　处：《肿瘤防治研究》2011年第3期322-323,共2页Cancer Research on Prevention and Treatment

摘　　要：目的探讨微波消融(PMCT)治疗中晚期肝癌对肝纤维化五项指标的影响。方法 49例微波消融的原发性肝癌患者,观察治疗前后血清HA、LN、PC-Ⅲ、Ⅳ-C、TGF-β1五项肝纤维化指标水平。结果 PMCT治疗后与PMCT治疗前相比,HA、LN、PC-Ⅲ、Ⅳ-C差异无统计学意义,TGF-β1每次均有下降(P<0.05)。结论 PMCT治疗原发性肝癌对HA、LN、PC-Ⅲ、Ⅳ-C无影响,且对肝纤维化有一定抑制作用。Objective To study the influence of the percutaneous microwave coagultion therapy（PMCT） on five hepatofibrosis indexes of middle and advanced hepatocellular carcinoma.Methods Forty-nine cases of primary hepatocellular carcinoma（massive type or nodular type） who had received curation of PMCT,hepatofibrosis index levels of serum HA、LN、PC Ⅲ、IV-C、TGF-β1 were observed before and after therapy.Results No significance difference was observed in relation to HA、LN、PC Ⅲ、IV-C of patients before and after every duration of PMCT.But the TGF-β1 was continuously reduced（P0.05）.Conclusion The HA、LN、PC-Ⅲ、Ⅳ-C were not significantly changed after PMCT,but the TGF-β1 was continuously reduced.

关 键 词：原发性肝癌 微波消融 肝纤维化 

分 类 号：R735.7[医药卫生—肿瘤] R730.56[医药卫生—临床医学]