高同型半胱氨酸血症对2型糖尿病合并急性脑梗死患者的影响研究  

Effects of Hyperhomocysteinemia in Parents of Acute Cerebral Infarction with Type 2 Diabetes Mellitus

作　　者：张庆梅[1] 李新华[1] 纪别克[1] 蒲瑜[1] 周明江[1] 

机构地区：[1]新疆石河子市人民医院神经内科,832000

出　　处：《实用心脑肺血管病杂志》2011年第4期551-552,共2页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘　　要：目的研究高同型半胱氨酸血症对2型糖尿病合并急性脑梗死患者的影响。方法采用酶联免疫法,对43例2型糖尿病性急性脑梗死患者和50例非糖尿病性急性脑梗死患者及65例对照者,进行血清Hcy含量检测。结果糖尿病性脑梗死患者同型半胱氨酸含量为(28.07±14.86)μmol/L,显著高于非糖尿病性脑梗死患者的(20.18±6.21)μmol/L,差异有统计学意义。均显著高于对照组同型半胱氨酸含量。结论高同型半胱氨酸血症是2型糖尿病并发脑梗死的一个重要危险因素。Objective To study the relationship between hyperhomocysteinemia and patients of acute cerebral infarction with type 2 diabetes mellitus.Methods In 43 patients of acute cerebral infarction with type 2 diabetes mellitus,50 patients of acute cerebral infarction with non-diabetes mellitus and 65 healthy controls.the level of plasma hcy was measured by enzymatic cycling assay.Results The level of hcy in group of acute cerebral infarction with type 2 diabetes mellitus（（28.07±14.86）μmol/L） was much higher than that non-diabetes mellitus（（20.18±6.21）μmol/L）.which higher than that of healthy controls.Conclusion Hyperhomocysteinemia is the importent risk factor in parents of acute cerebral infarction with type 2 diabetes mellitus.

关 键 词：高同型半胱氨酸血症 2型糖尿病 急性脑梗死 

分 类 号：R743.3[医药卫生—神经病学与精神病学]