松龄血脉康对急性心肌梗死再灌注后左室重构和心功能影响研究  

Reperfusion in Acute Myocardial Infarction Left Ventricular Remodeling and Cardiac Function of Xuemaikang

作　　者：阮蕾[1] 秦方[1] 付莉[1] 汤雁蓉[1] 王静[1] 郑铿[1] 张静[1] 陈航[1] 刘童[1] 唐高[1] 

机构地区：[1]四川省成都市第一人民医院心内科,610000

出　　处：《实用心脑肺血管病杂志》2011年第4期573-574,共2页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘　　要：目的研究松龄血脉康对急性心肌梗死(AMI)成功再灌注后左室重构和心功能的影响。方法 95例AMI患者再灌注治疗后随机分为松龄血脉康组(48例)和对照组(47例),松龄血脉康组在常规治疗的基础上加服中药松龄血脉康,对照组为常规治疗。观察AMI后30d及6个月的左室射血分数(LVEF)和舒张末容积(LVEDV)。结果两组患者年龄、性别、梗死部位和大小,再灌注治疗的时间均无显著性差异。松龄血脉康组30d时LVEDV明显小于对照组,6个月时进一步减小;LVEF30d时两组虽无差异,但6个月时松龄血脉康组明显高于对照组。NT-proBNP的水平松龄血脉康组30d时即显著低于对照组,6个月时更加明显。结论 AMI患者实施再灌注治疗后松龄血脉康可以改善近期和远期的左室重构和左心功能。Objective This study will evaluate the role of xumaikang in the prevention of left ventricular remodeling and cardiac functional improvement.Methods 95 AMI patients were sellected and assigned randomally to xuemaikang group（regular medication and xuemaikang） and control group（regular medication）.Left ventricular ejection fraction（LVEF） and left venticular end diastolic volume（LVEDV） were measured at day 30 and six-month post AMI.Results There were not significant between two group in age sex and infarction area,as well as time for repefusion.LVEDV in xuemaikang group was significantly lower than control group,with a further reduction at six-month.LVEF was higher in xuemaikang group than control.In xmk group,NT-proBNP was much lower than control both at day 30 and six-month.Conclusion Xuemaikang can improve cadiac function and left ventricular remodeling after AMI.

关 键 词：松龄血脉康 急性心肌梗死 左室重构 

分 类 号：R743.3[医药卫生—神经病学与精神病学]