涎腺癌颈淋巴结转移的临床分析  

Cervical lymph node metastasis in salivary gland carcinoma

作　　者：彭歆[1] 郝杨 高敏[1] 陈艳[3] 高岩[3] 马大权[1] 俞光岩[1] 

机构地区：[1]北京大学口腔医学院口腔颌面外科,北京100081 [2]北京大学口腔医学院第二门诊部,北京100081 [3]北京大学口腔医学院病理科,北京100081

出　　处：《中国耳鼻咽喉头颈外科》2011年第3期118-120,共3页Chinese Archives of Otolaryngology-Head and Neck Surgery

摘　　要：目的了解涎腺癌颈淋巴结转移的发生情况,为临床治疗提供参考。方法选择北京大学口腔医学院具有完整临床及随访资料的涎腺癌患者815例,记录颈部淋巴结转移情况,分析涎腺癌的颈淋巴结转移的发生规律。结果 815例涎腺癌患者的总体颈淋巴结转移发生率11.53%(94/815)。颈淋巴结转移发生率位列前3位的肿瘤分别是鳞状细胞癌、透明细胞癌、淋巴上皮癌和涎腺导管癌(并列位居第3),发生率较低的肿瘤类型是腺泡细胞癌和多形性低度恶性腺癌。来自颌下腺癌患者的颈淋巴结转移发生率明显高于腮腺和舌下腺患者(P<0.05)。T3、T4级患者的颈淋巴结转移发生率明显高于T1、T2级患者(P<0.05)。结论肿瘤大小、病理类型、分化程度和原发部位是涎腺癌颈淋巴结转移的重要影响因素。OBJECTIVE To investigate the characteristics of cervical lymph node metastasis in salivary gland carcinoma.METHODS The clinical data of 815 cases with salivary gland carcinomas in Peking University School and Hospital of Stomatology were reviewed.The influence factors including histopathology type,tumor grade,primary site, tumor size were analyzed.RESULTS The overall rate of cervical lymph node metastasis in salivary gland carcinoma was 11.53%（94/815）.The？rst three histopathology types with highest rate were squamous cell carcinoma,clear cell carcinoma,lymphoepithelial carcinoma and salivary duct carcinoma.The histopathology types with lowest rate were acinic cell carcinoma and polymorphous low-grade adenocarcinoma.The rate is significantly higher in submandibualr gland carcinoma than in parotid and sublingual gland（P0.05）.The higher rate was noted in the patients with T3 and T4 than T1 and T2 （P0.05）.CONCLUSION Histopathology type,tumor size,tumor grade and primary site are the important factors for the cervical lymph node metastasis in salivary gland carcinoma.

关 键 词：涎腺肿瘤 淋巴转移 外科 口腔 预后 

分 类 号：R739.8[医药卫生—肿瘤]