汗管样小汗腺癌国内首报  

Syringoid Eccrine Carcinoma:The First Case Report in China

作　　者：刘彤云[1] 柴燕杰[1] 李霞[2] 杨汝斌[1] 万屏[1] 何黎[1] 王正文[1] 

机构地区：[1]昆明医学院第一附属医院皮肤科,云南昆明650032 [2]云南省开远市人民医院皮肤科,云南开远661600

出　　处：《中国皮肤性病学杂志》2011年第4期247-249,共3页The Chinese Journal of Dermatovenereology

摘　　要：患者女,56岁。右口角斑块2年余。皮肤科情况:右口角见一2.2cm×1.4cm浸润性肤色斑块,中央偏淡红色,表面不平,边界清楚,与皮肤黏连,质硬。组织病理检查示:真皮中下部及皮下组织见多数基底样瘤细胞团块,瘤细胞形成巢状、条索状或蝌蚪样肿瘤团块,伴有大量管腔及囊腔样结构形成,部分腔内可见嗜酸性均一物质。间质明显增生,可见透明变性和黏液变性。未见角质囊肿及筛状结构形成。免疫组化染色示:肿瘤细胞上皮膜蛋白(EMA)和癌胚抗原(CEA)阳性,S100蛋白、角蛋白10(CK10)、角蛋白20(CK20)和GCDFP-15(gross cystic disease fluid protein-15)均阴性。诊断:汗管样小汗腺癌。本病临床罕见。治疗采用Mohs手术切除。A 56-year-old woman presented with 2 years history of a 2.2cm×1.4cm skin-color firm plaque beside the right cheilion.The lesion was well-demarcated and fixed to the underlying tissue.The tumour consisted of atypical basaloid cells arranging in narrow cords and nests and partially forming ductular,adenoid and cystical structure in dermis and subcutaneous adipose tissue.Tadpole-like forms were observed.Squamous or follicular differentiation was not seen.Tumour cells showed positive reactivity to EMA and CEA but negative to S-100 protein,CK10,CK20 and GCDFP-15.Diagnosis：Syringoid eccrine carcinoma.This is an extremely uncommon case.The patient was treated with Mohs micrographic surgery.

关 键 词：汗管样小汗腺癌 诊断 治疗 

分 类 号：R739.5[医药卫生—肿瘤]