无抽搐电痉挛治疗抽搐发作质量纵向观察  

The Longitudinal Study of Seizure Quality of Modified Electroconvulsive Therapy in Convulsive Seizure

作　　者：刘知源[1] 周小东[1] 付华斌[1] 朱宏日[1] 祁革[1] 宁卫东[1] 田晓馨[1] 赵云云[1] 

机构地区：[1]解放军白求恩国际和平医院256临床部精神科,河北正定050800

出　　处：《解放军医药杂志》2011年第2期32-33,共2页Medical & Pharmaceutical Journal of Chinese People’s Liberation Army

摘　　要：目的纵向观察无抽搐电痉挛治疗（MECT）过程中抽搐发作质量随着治疗次数增加的变化趋势。方法选择106例在我院精神科顺序住院的精神疾病患者,排除MECT禁忌证,给予1~8次MECT。采用抽搐发作时间（EEG seizure du-ration,ESD）、平均抽搐发作能量指数（average seizure energy index,ASEI）、发作后抑制指数（postictal suppression index,PSI）和最大持续一致性（maximum sustained coherence,MSC）等指标评估每次MECT治疗后的抽搐发作质量。结果除MSC外,ESD、ASEI和PSI均呈下降趋势（P〈0.01）。结论对MECT治疗效果不理想的患者可能需要关注抽搐发作质量。Objective To observe the longitudinal changes of seizure quality of modified electroconvulsive therapy（MECT） along with increasing of treatment time.Methods 106 mental disorder patients without MECT contraindication were admitted to Psychiatry Department sequentially and treated with MECT 1 to 8 times.EEG seizure duration（ESD）,average seizure energy index（ASEI）,postictal suppression index（PSI） and maximum sustained coherence（MSC） were assessed during each treatment of MECT.Results Except MSC,other indexes,including ESD,ASEI and PSI,declined significantly（P0.01）.Conclusion Close attention should be paid to seizure quality in case of poor efficacy in the course of MECT treatment.

关 键 词：无抽搐电痉挛治疗 抽搐发作质量 纵向研究 

分 类 号：R749.05[医药卫生—神经病学与精神病学]