银杏达莫注射液(杏丁)治疗血管性痴呆前后的经颅多普勒改变  

The study of Transcranial Doppler for treating vascular dementia with Ginkgo Leaf Extract And Dipyridamole Injection(xingding)

作　　者：符鹏程[1] 陈继华[1] 雷生锁[1] 姚小喜[1] 

机构地区：[1]湖南省郴州市第一人民医院神经内科,423000

出　　处：《中国医疗前沿》2011年第6期76-77,共2页China Healthcare Innovation

摘　　要：目的观察银杏达莫注射液(杏丁)在治疗血管性痴呆患者中的疗效。方法选择58例老年血管性痴呆患者随机分成治疗组和对照组,对照组(29例)应用常规治疗,治疗组(29例)在常规治疗基础上加用银杏达莫治疗,2周为1疗程,共治疗2个疗程。治疗前后分别采用简易精神状态检查量表(MMSE)、改良长谷川痴呆量表(HDS-R)和经颅多普勒(TCD)进行评价。结果治疗后治疗组MMSE、HDS-R评分高于对照组(P<0.05);治疗组治疗后TCD血流速度较对照组有明显提高(P<0.05)。结论银杏达莫注射液能明显改善血管性痴呆患者的认知功能,提高脑动脉血流速度。Objective To observe the effect of Ginkgo Leaf Extract And Dipyridamole Injection（xingding） in treatment of vascular dementia.Methods 58 patients with vascular dementia were randomly divided into two groups.29 patients in the control group were treated with routine therapy.29 patients in the treatment group were treated with Ginkgo Leaf Extract And Dipyridamole Injection（xingding） along with routine therapy.All treatments lasted two therapeutic course,each course included two weeks.Mini-Mental Status Examination（MMSE）,Revised Hasegawa Dementia Scale（HDS-R） and transcranial doppler（TCD） were used to evaluate the curative effects before and after treatments.Results After treatments,the MMSE and HDS-R score of the treatment group was higher than the control group（P0.05）,the cerebral blood flow velocity of the treatment group was higher than the control group（P0.05）.Conclusion Ginkgo Leaf Extract And Dipyridamole Injection（xingding） can improve cognitive functions and the cerebral blood flow velocity of patients with vascular dementia.

关 键 词：银杏达莫 血管性痴呆 简易精神状态检查量表 改良长谷川痴呆量表 TCD 

分 类 号：R749.13[医药卫生—神经病学与精神病学]