调节因素与年龄相关性白内障发病的关系  

The relationship between adjustment factors and age-related cataract morbidity

作　　者：高婧[1] 黄旭东 姜雅琴 

机构地区：[1]滨州医学院临床学院,滨州市256603 [2]潍坊眼科医院

出　　处：《滨州医学院学报》2011年第2期105-107,共3页Journal of Binzhou Medical University

摘　　要：目的探讨年龄相关性白内障发病与调节的关系,为年龄相关性白内障发病机制的研究及治疗提供理论依据。方法选取双眼白内障程度相近的病例30例共60只眼,分别于术前及术后1周测量主视眼,术前测量在自然状态下和缩瞳后的晶体厚度,取术中撕取的中央部晶体前囊膜做HE染色,进行细胞计数。结果 30例术前术后未出现主视眼转换情况,主视眼和非主视眼在自然状态下和缩瞳后的晶体厚度变化差值有统计学意义(P(0.01),主视眼和非主视眼的晶体囊膜上皮细胞密度分别为(3606±429)个/mm2和(3913±433)个/mm2,其差别有统计学意义(P(0.01)。结论主视眼因为在日常视觉活动中动用的调节度大,进入眼内的光线量大,可能因此造成了晶体囊膜上皮细胞数目的减少,导致其白内障发病先于非主视眼。Objective To discuss the relationship betueen age-related cataract morbidity and the adjustment to provide the theory basis for the research and the treatment of age-related cataract pathogenesis.Methods Sixty eyes of thirty patients with close cataract degrees were chosen and the dominant eyes were measured a week before and after the surgery.The lens thicknesses were measured before the surgery at the natural state and the miosis state,and part of the anterior membrane of the central lens was ripped during the surgery and stained with HE Method and cell numbers were counted.Results Before and after the surgery,the dominant eyes of the 30 cases didn＇t change,and the changes of the lens thicknesses of the dominant eyes and the non-dominant eyes at the natural state and the miosis state had remarkable difference（P0.01）.The epithelial cell density of the lens membrane of the dominant eyes and the non-dominant eyes were（3606±429）/mm2 and（3913±433）/mm2 respectively and its difference had remarkable significance statistically（P0.01）.Conclusions The dominant eye is used with higher adjustment degree and with larger amount of light in the daily visual activities,which leads to the reduction of epithelial cell numbers of lens membrane and its cataract morbidity earlier than the non-dominant eye.

关 键 词：调节 主视眼 年龄相关性白内障 晶体厚度 上皮细胞 

分 类 号：R776.1[医药卫生—眼科]