古今肺痿方的配伍规律研究  

Study on Compatibility Laws of Past and Present Formulae for Consumptive Lung Disease

作　　者：陶静[1,2] 范欣生[1,2] 杨环[1] 尚尔鑫[2] 刘正[3] 

机构地区：[1]南京中医药大学中医药文献研究所,江苏南京210046 [2]南京中医药大学江苏省方剂重点实验室,江苏南京210046 [3]南京大学计算机软件新技术国家重点实验室,江苏南京210093

出　　处：《中国中医药信息杂志》2011年第5期20-22,共3页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：江苏省中医药局康缘创新基金(HZ0801KY);江苏省教育厅重点研究项目(06KJA36022)

摘　　要：目的运用数据挖掘方法,分析肺痿方单味药、药对之间的关联关系,探讨肺痿方的配伍规律。方法收集肺痿方261首,针对古今肺痿方药物配伍和药对特征,对单味药、药对之间的关联关系,分别采用频繁模式、Apriori算法进行分析。结果古今医家治疗肺痿时常选用的药物多具有化痰止咳平喘、补气养阴生津的功效,如桔梗、杏仁、五味子、人参、麦冬等;现代医家对于药物的选择比古代医家更为集中,同时常使用古代医家很少用到的药物,如丹参、当归、川芎等。结论在肺痿方剂的运用中,古今医家在高频药物的使用方面具有明显的差异性。Objective To discover the association relations of the single herbs and herb-pairs of formulae for consumptive lung disease by data mining method to analyze and study the compatibility laws of the prescriptions. Method Based on the features of the herb-pair and compatibility of the past and present formulae used for consumptive lung disease, 261 formulae for consumptive lung disease were collected to detect association relations of the single herbs and herb-pairs by frequent pattems and Apriori algorithm respectively. Result The herbs most commonly used by physicians of past generations have the function of dissolving phlegm, suppressing cough, relieving asthma, tonifying qi, nourishing yin and generating fluid, such as Radix Platycodi, Semen Armeniacae Amarum, Fructus Schisandrae Chinensis, Panax ginseng, Radix Ophiopogonis, etc. The modem physicians chose the herbs more concentrated than the ancient physicians, and in the meantime, they often used some herbs rarely used by the ancient physicians, such as Radix Salviae Miltiorrhizae, Angelica sinensis, Rhizoma Chuanxiong, etc. Conclusion It is significantly different between the ancient and modem physicians in using herbs with a higher frequency in formulae for treating consumptive lung disease.

关 键 词：肺痿方 配伍规律 数据挖掘 APRIORI算法 

分 类 号：R2-05[医药卫生—中医学]