胃肠道间质瘤58例临床分析  

Clinical Analysis of 58 Cases of Gastrointestinal Stromal Tumors

作　　者：付忠平[1] 

机构地区：[1]湖南省肿瘤医院腹外一科,湖南长沙410013

出　　处：《医学临床研究》2011年第4期723-725,共3页Journal of Clinical Research

摘　　要：【目的】探讨胃肠道间质瘤（GIST）的临床特点，诊断和治疗。【方法】回顾分析2003年1月至2009年10月本院58例GIST患者临床资料。【结果]GIST好发胃和小肠，临床表现缺乏特异性。CD117阳性率为94．8％。全组均行手术治疗，54例获完整切除。术后14例接受伊马替尼治疗。全组1、3、5年生存率分别为96．2％、82．4％、72．2％。【结论】GIST的确诊依靠病理和免疫组化检查，CD117对诊断有重要作用。手术切除是主要治疗方法，术后辅助伊马替尼治疗能提高疗效。[Objective] To explore the clinical features, diagnosis and treatment of gastrointestinal stromal tumors（GIST）. [Methods] The clinical data of 58 cases with GIST in our hospital from Jan. 2003 to Oct. 2009 were analyzed retrospectively . [Results] Most of GIST were originated from stomach and small intestine, and the lack of specific clinical manifestation. All of these patients underwent surgical treatment, and 54 cases of them underwent complete tumor resection. After surgery, 14 patients were given imatinib. The 1-, 3-, 5-year survival rates of all patients was 96.2%, 82.4% and 72.2%. [Conclusion] The definite diagnosis of GIST relies on pathological and immunohistochemieal examination, CD117 is an important marker for the diagnosis of GIST. Surgical resection is the main method. Postoperative adjuvant therapy with imatinib can improve the curative effect.

关 键 词：胃肠肿瘤 间皮瘤 

分 类 号：R735[医药卫生—肿瘤]