非小细胞肺癌和食管癌微血管密度的检测意义  

The Detective Significance of Microvascular Density in Non-Small-Cell Lung Cancer and Esophageal Carcinoma

作　　者：张晓飞[1] 刘艳梅[1] 刘立群[1] 丛绪滋[1] 

机构地区：[1]苍山县人民医院,山东苍山277700

出　　处：《肿瘤基础与临床》2011年第2期109-111,共3页journal of basic and clinical oncology

摘　　要：目的探讨微血管密度(MVD)在判断非小细胞肺癌及食管癌患者预后方面的价值。方法入组手术治疗的34例非小细胞肺癌和81例食管癌患者,用免疫组化法检测肿瘤标本的MVD,分析检测结果与预后的关系。结果非小细胞肺癌MVD只对总生存期有独立预测意义;食管癌MVD对术后无病生存期及总生存期均具有独立预测意义。结论 MVD是非小细胞肺癌和食管癌的独立预后因子。Objective To study the predictive value of microvascular density（MVD） in determining the prognoses of non-small-cell lung cancer and esophageal carcinoma.Methods This study included 34 patients with non-small-cell lung cancer and 81 patients with esophageal carcinoma.MVD was detected using immunohistochemical methods in order to find the correlation between MVD and prognosis of the patients.Results Of the patients with non-small-cell lung cancer,MVD was an independent predicator for overall survival time.Of the patients with esophageal carcinoma,MVD was an independent predicator for disease free survival time and overall survival time.Conclusion MVD may be an independent predicator for non-small-cell lung cancer and esophageal carcinoma.

关 键 词：非小细胞肺癌 食管癌 微血管密度 预后 

分 类 号：R734.2[医药卫生—肿瘤] R735.1[医药卫生—临床医学]