色素放大内镜下Barrett食管微细结构的分析  

Ultrastructural analysis of Barrett＇s esophagus under magnifying chromoendoscopy

作　　者：严山[1] 凌红[1] 杨伟平[1] 徐永成[1] 王红[1] 

机构地区：[1]惠州市中心人民医院消化内科,广东省惠州516001

出　　处：《中国基层医药》2011年第6期736-738,共3页Chinese Journal of Primary Medicine and Pharmacy

基　　金：广东省惠州市科技项目（2010Y007）

摘　　要：目的研究色素放大内镜下Barrett食管（BE）微细结构的变化及与病理组织学的相关性，提高BE镜下诊断。方法应用放大内镜对疑似BE黏膜进行染色放大观察并做病检，记录67例经病理确诊BE病例的临床表现、内镜特点及病理分型。结果BE的内镜分型：岛型28例，舌型7例，全周型32例。放大内镜共分三型，其中Ⅲ型病理均为肠上皮化生，肠化生检出率与Ⅰ型、Ⅱ型比较差异有统计学意义（x^2=21．8，P〈0．01）。结论色素内镜在Barrett食管的诊断和组织学较常规内镜有较好的一致性。Objective To study Barrett＇s esophageal consistency with its histological findings, which were found with magnifying chromoendoscopy,and to advance the endoscopic diagnosis of Barrett＇s esophagus. Methods The patients with BE were diagnosed by endoscopy and histology, and their histological findings and endoscopic appearances of a total of 67 patients with BE were observed. Results Endoscopic appearances type of BE showed island（28 cases） ,tongue（7 cases） ,and circum ference（ 32 cases）. Three types of BE under magnifying chromoendoscopy,and in magnifying endoscope group ,type III which were found with magnifying endoscope were verified intestinalisation epithelium patho-type, compared with type I and type II, the discrepancy of them had statistical significance（ P 〈 0.01 ）. Conclusion Magnifying chromoendoscopy had a relatively better consistency in the diagnosis of Barrett＇s esophagus with histological findings.

关 键 词：BARRETT食管 胃肠内窥镜 病理学 

分 类 号：R57[医药卫生—消化系统]