癌症患者生命质量测定量表体系中各量表的测量学特性分析  

Study on psychometrical characteristics of different scales among instruments measuring quality of life for patients with cancer

作　　者：孟琼[1] 万崇华[2] 罗家洪[1] 汤学良[3] 李云峰[4] 寸英丽[5] 

机构地区：[1]昆明医学院公共卫生学院流行病与卫生统计学系,昆明650031 [2]广东医学院人文与管理学院,东莞523808 [3]云南省肿瘤医院乳腺科,昆明650118 [4]云南省肿瘤医院大肠癌临床研究中心,昆明650118 [5]云南省肿瘤医院腹部外科,昆明650118

出　　处：《肿瘤》2011年第3期245-249,共5页Tumor

基　　金：云南省社会发展科技计划项目(编号:2008CD055)

摘　　要：目的:分析癌症患者生命质量测定量表体系(Quality of Life Instruments for Cancer Patients, QLICP)中,已研制的用于测定肺癌、乳腺癌、头颈癌、胃癌、结直肠癌和宫颈癌等6种癌症患者的量表构成及信度、效度和反应度。方法:采用量表开发的程序化方法研制各量表,然后对692例恶性肿瘤(包括85例肺癌、186例乳腺癌、133例头颈癌、86例胃癌、110例结直肠癌和92例宫颈癌)患者进行生命质量测定,通过计算总量表及各领域的克朗巴赫系数α和重测相关系数,应用探索性因子以及采用配对t检验等分析方法,考评研制量表的信度和效度。结果:6种癌症患者的生命质量测定量表均有较好的结构和符合要求的测量学特性,即有较好的信度、效度和一定的反应度。结论:肺癌、乳腺癌、头颈癌、胃癌、结直肠癌和宫颈癌等6种癌症的特异模块与QLICP体系中的共性模块结合后,可用于临床上相应癌症患者生命质量的测定。Objective：To analyze the structure,reliability,validity and responsiveness of the six scales in the system of instruments measuring quality of life for patients with cancer（QLICP）,which were developed to assess the quality of life for the patients with lung cancer,breast cancer,head and neck cancer,stomach cancer,colorectal cancer and cervical cancer.Methods：By using a stylized method,six QLICP-scales for lung cancer,breast cancer,head neck cancer,stomach cancer,colorectal cancer and cervical cancer were developed.The quality of life of 692 patients with different tumors including lung cancer（n=85）,breast cancer（n=186）,head neck cancer（n=133）,stomach cancer（n=86）,colorectal cancer（n=110） and cervical cancer（n=92） were measured.The reliability,validity and the responsiveness of the six scales were evaluated by calculating the Cronbach＇s α coefficient for the overall and each domain of the scale,calculating the test-retest reliability coefficient,and using exploratory factor analysis and the paired t-test.Results：All of the six scales in the system of QLICP have good structure and satisfactory psychometrics characteristics,which means that they have good reliability,validity and the tolerable responsiveness.Conclusion：The six special modules in the system of QLICP,including lung cancer,breast cancer,head and neck cancer,stomach cancer,colorectal cancer and cervical cancer modules,can be used in combination with general module of QLICP as the instrument to assess the quality of life for patients with different cancers.

关 键 词：肿瘤 健康状况指标 生物统计学 生活质量 评定量表 

分 类 号：R73-31[医药卫生—肿瘤] R730.7[医药卫生—临床医学]