1,6二甲基-3-苄基脲嘧啶类化合物的合成及除草活性  

Synthesis and Herbicidal Activity of 3-Benzyl-1,6-Dimethyluracil Derivatives

作　　者：李公春[1] 张建立[1] 朱凤祥[1] 杨风岭[1] 

机构地区：[1]许昌学院化学化工学院,河南许昌461000

出　　处：《湖北农业科学》2011年第8期1584-1586,共3页Hubei Agricultural Sciences

基　　金：河南省自然科学基金项目(082300420110);河南省教育厅自然科学基金项目(2007150036)

摘　　要：6-甲基-3-苄基脲嘧啶类化合物与硫酸二甲酯在无水碳酸钾作敷酸剂及N,N-二甲基甲酰胺作溶剂条件下室温反应,尿嘧啶环上1-位氢原子被甲基取代。合成了3种1,6-二甲基-3-苄基脲嘧啶类化合物,所合成的目标化合物均通过1H NMR和元素分析确证。生物活性测试表明该类化合物有一定的除草活性,化合物b浓度100μg/mL时对油菜根长生长抑制和稗草株高生长抑制具有较好的效果。When 3-benzyl-6-methyluracil derivatives reacted with dimethyl sulfate with the presence of anhydrous potassium carbonate,using N,N-dimethylformamide as solvent,1-position hydrogen of uracil ring was substituted by methyl.Three 3-benzyl-1,6-dimethyluracil derivatives were synthesized;and all compounds were confirmed by 1H NMR and elementary analysis.The herbicidal activities of these compounds were examined;and the biological test showed that compound b had good anti Brassica napus and Echinochloa crusgalli（L.） Beauv.activity at the concentration of 100 μg/mL.

关 键 词：1 6-二甲基-3-苄基脲嘧啶 合成 除草活性 

分 类 号：O626.4[理学—有机化学] S482.4[理学—化学]