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作 者:袁振华[1] 丁友昌[1] 陈筱君[1] 王明法[1] 杨章萍[1]
机构地区:[1]杭州市卫生防疫站,杭州310006
出 处:《癌变.畸变.突变》1999年第5期272-275,共4页Carcinogenesis,Teratogenesis & Mutagenesis
摘 要:本次研究采用了两组模拟装饰实验室,应用化学方法检测室内挥发性化学物的浓度及消除情况,同时在国内首次应用环境生物检测技术- 蚕豆叶尖细胞微核试验,发现了装饰材料中挥发性化学物的潜在致突变性,并与哺乳动物的遗传毒性有很好相关性。根据研究结果,获得居住者的最安全的接触时间,并首次提出了新装修居室的空气卫生标准建议值,为卫生部门制订有关标准提供科学依据。The concentration and disappearance of the indor volatile organic compounds(VOC) was measured by chemical mothods under two model ornamented laboratory condition. The potential mutagenicity of VOCs was measured by the micronucleus test in vicia faba leaf tips. The results showed that the VOCs in ornamental materials had the potential mutagenicity. The results of micronucleus test had obvious relationship comparing with the genotoxicity of mouse. The moicronucleus test in vicia faba leafs tips and mouse bone marrow cell suggested that human were safe coming into the new ornamental room after one month. This paper recommend the sanitation standard values of the air in new ornamental houses first of all in our country. Our study provided the sientific basis of establishing health standard for the department of health.
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