植入性胎盘产前诊断  

Prenatal Diagnosis of Placenta Accreta

作　　者：邹晓琴[1] 叶卫莲[1] 黄友琼[1] 吴京[1] 李丹妍[1] 

机构地区：[1]汕头大学医学院第二附属医院妇产科,广东汕头515000

出　　处：《河北医学》2011年第5期629-631,共3页Hebei Medicine

摘　　要：目的:探讨植入性胎盘的产前诊断方法,更好的降低分娩风险。方法:选取2007年1月至2009年12月在我院分娩、经临床及病理确诊为植入性胎盘的患者23例,随机选择同期非植入性胎盘的孕产妇30例,两组孕产妇产前均检查彩色多普勒、血清肌酸酶(CK)、血清甲胎球蛋白(AFP),比较两组孕妇的检查结果。结果:植入性胎盘组产前彩色多普勒提示植入性胎盘患者13例(56.5%),血清肌酸酶(CK)升高14例(60.9%),血清甲胎球蛋白(AFP)升高17例(73.9%),比例均明显高于非植入性胎盘组,差异有统计学意义(P<0.01);植入性胎盘组患者经恰当有效的保守及非保守治疗,均取得满意的疗效,无孕产妇及婴儿死亡。结论:植入性胎盘可通过彩色多普勒超声检查、血清肌酸激酶(CK)及血清甲胎球蛋白(AFP)的检测进行产前诊断,对彩色多普勒超声无法诊断的植入性胎盘,一旦血清肌酸激酶(CK)或血清甲胎球蛋白(AFP)升高,也应警惕植入性胎盘的存在;彩色多普勒超声检查、血清肌酸激酶(CK)及血清甲胎球蛋白(AFP)的检测可显著提高植入性胎盘的产前诊断率,明显降低分娩风险。Objective：To investigate the prenatal diagnosis of placenta,futher reduce risk of delivery.Method：Experimental group included 23 cases of placenta accreta who delivered form in our hospital Jan.2007 to Dec.2009,diagnosed by clinical and pathological;Control group included 30 cases randomly selected of placenta accreta in the same period.belly color doppler ultrasonography,the serum enzyme creatine（CK） and serum fetoprotein（AFP） of the two groups were detected and compared α before delivery.Results：Prenatal doppler examination of experimental group prompted 13 patients with placenta accreta（56.5%）,serum creatine enzyme（CK） increased in 14 cases（60.9%）,serum α fetoprotein（AFP） rised in 17 cases（73.9%）,significantly higher than the proportion of control group.The difference was statistically significant（p 〈0.01）;patients with placenta accrete accept appropriate and effective conservative and non conservative treatment,with satisfactory efficacy,outcome no maternal and infant death.Conclusion：The implantation of the placenta could be detected by color doppler ultrasonography,serum creatine kinase（CK） and serum α fetoprotein（AFP） testing for prenatal diagnosis.If color doppler ultrasound could not found placenta accreta,It should be guarded when serum creatine kinase（CK） or serum α fetoprotein（AFP） increased.Color doppler ultrasound examination,serum creatine kinase（CK） and serum α fetal ball protein（AFP） detection can significantly improve prenatal diagnosis of placenta accreta rate,significantly reduce risk of childbirth.

关 键 词：植入性胎盘 产前诊断 

分 类 号：R714.462[医药卫生—妇产科学]