F波在糖尿病周围神经病中的诊断价值  

The value of F wave in the diagnosis of diabetic peripheral neuropathy

作　　者：张淑平[1] 冯立群[1] 曲秋菊[1] 

机构地区：[1]首都医科大学附属北京安贞医院神经内科,100029

出　　处：《中国神经免疫学和神经病学杂志》2011年第3期211-213,224,共4页Chinese Journal of Neuroimmunology and Neurology

摘　　要：目的探讨F波在糖尿病周围神经病(DPN)中的诊断价值。方法收集作者医院的糖尿病患者100例,根据有无周围神经病变临床和体征分为临床DPN组(60例)和亚临床DPN组(40例),另选健康对照组50名。采用肌电图诱发电位仪检测各组F波最短潜伏期(Flmi)、F波潜伏期离散度(Fchd)、F比值(Fratio)、F波出现率(Fpresent)、F波波幅(Famp),并进行比较。结果 100例糖尿病患者中F波未引出2例(2%),F波Flmi延长33例(33%),临床DPN组Flmi异常率(41.7%)高于亚临床DPN组(20.0%)(P<0.05)。与对照组比较,临床DPN组和亚临床DPN组Fchd升高(P<0.05),Famp和Fpresent均降低(P<0.05)。临床DPN组与亚临床DPN组比较Fchd、Famp无统计学差异(P>0.05),而临床DPN组Fpresent较亚临床DPN组低(P<0.05),3组间Fratio比较无统计学差异(P>0.05)。F波各参数总异常率与尺神经运动传导各参数总异常率无统计学差异。结论 F波多个参数的测定有助于DPN的早期诊断,并有助于揭示亚临床病灶。Objective To explore the value of F wave in the diagnosis of diabetic peripheral neuropathy. Methods One hundred patients with non insulin-dependent diabetes mellitus （NIDDM） were divided into clinical group （60 cases） and subclinical group （40 cases）, according to whether peripheral neuropathy was present, and the healthy control （50 cases） was also included. The shortest latency （Flmi）, dispersion （Fchd）, ratio （Fratio）, appearance rate （Fpresent）, and amplitude （Famp） of F waves were detected and these parameters were analyzed with t or x^2 test. Results In the 100 NIDDM patients, 2 cases （2%） did not show F wave, 33 eases （33%） had longer Flmi, and Flmi abnormal rate in clinical group （41.7%） was higher than that in subclinical group （20.0%） （P〈0.05）. Compared with the healthy control, both clinical and subclinical groups had bigger Fchd, lower Famp and less Fpresent （P〈0.05）. There was no significant difference in Fchd and Famp between clinical group and subclinical group （P〉0.05）. The Fpresent in clinical group is lower than that in subclinical group （P〈0.05）. Among these three groups, there was no significant difference in Fratio （P〉 0.05）. There were no significant difference in the overall abnormal rate between F wave and the ulnar nerve motor conduction. Conclusions F wave determination can help us to diagnose early diabetic peripheral neuropathy and find sub clinical cases.

关 键 词：糖尿病 周围神经 F波 

分 类 号：R747.9[医药卫生—神经病学与精神病学]