眼球表面鳞状细胞性肿物的临床病理学分析  

The clinicopathological analysis of ocular surface squamous neoplasia.

作　　者：林锦镛[1] 李恩江[1] 陈瑰 

机构地区：[1]天津眼科医院,300040

出　　处：《中国实用眼科杂志》1999年第10期589-592,共4页Chinese Journal of Practical Ophthalmology

摘　　要：目的:提高对眼球表面鳞状细胞性肿物的诊断和治疗水平。方法:对天津眼科医院1978～1997年收治的180例眼球表面鳞状细胞性肿物进行临床和病理学分析。结果:本组病变可分为三大类:1良性病变73例(40.4%),包括鳞状细胞增生、乳头状瘤和假上皮瘤样增生;2交界性病变42例(23.3%),主要是非典型增生;3恶性病变65例(35.9%),包括原位癌、鳞状细胞癌和粘液表皮样癌。本组病变好发于角膜缘部位(118例),男性多见(145例),通常为单眼发病,多数发病时间为半年～1年内。手术后复发主要与肿物切除不彻底有关。结论:对眼球表面鳞状细胞性肿物的术前正确诊断、手术设计和手术边缘的病理学检查是非常重要。To improve the level of diagnosis and treatment for ocular surface squamous neoplasia (OSSN).Methods:The 180 cases of OSSN treated in Tianjin Eye Hospital from 1978 1997 were analysed by clinical and pathological methods.Results:These lesions may divide into three types:(1)benign lesions 73 cases(40.4%),including squamous cell hyperplasia,papilloma,and pseudo epitheliomatous hyperplasia;(2)intermediate lesions 42 cases (23.3%),mainly dysplasia;(3)malignancy lesions 65 cases (35.9%),including carcinoma in situ,squamous cell carcinoma and muco epidermoid carcinoma.118 cases occured in limbus and 145 cases were males.The duration of symtomas of major cases ranged from 6～12 months.Recurrences were related to inadequate surgical margins.Conclusion:The accuracy diagnosis of preoperation,surgical design and pathological examination of surgical margins are very important.

关 键 词：眼球表面 鳞状细胞性肿物 诊断 临床病理学 

分 类 号：R739.7[医药卫生—肿瘤]