Synthesis and characteristics of pH-and temperature-sensitive hydrogels of poly （DMAEMA/NIPAAm）  

作　　者：QIAN Qi-ang CHEN Jie YANG Li-ming DING Guo-wei SHAN Ting JIE Shao-wei XING Su-jie 

机构地区：[1]Department of Chemical Engineering and Technology, School of Environmental and Chemical Engineering,Shanghai University, Jiading Shanghai 201800, China [2]Department of Oral ＆ Maxillofacial Surgery,Tongji Hospital, Tongji University, Shanghai 200092, China

出　　处：《Journal of Chemistry and Chemical Engineering》2008年第4期29-34,共6页化学与化工（英文版）

摘　　要：A kind of novel copolymer hydrogel of poly（N, N-dimethylaminoethyl methacrylate-co-N-isopropylacrylamide） （poly[DMAEMA/NIPAAm]） was synthesized by the initiation of K2S2O8, N, N＇-methylene-bis（acrylamide） （Bis） was used as the crosslinker. The effects of monomer content, pH and temperature on swelling ratio of the hydrogel were investigated; the thermo-sensitivity in deionized water and in physiological saline was determined. It showed that the swelling ratio of the hydrogel could be changed by changing the temperature or pH alternately. Both swelling ratio and LCST （Lower Critical Solution Temperature） of the hydrogel decreased with the increase of NIPAAm in the co-polymer content.

关 键 词：HYDROGEL N N-dimethylaminoethyl methacrylate N-ISOPROPYLACRYLAMIDE TEMPERATURE-SENSITIVE PH-SENSITIVE 

分 类 号：TQ342.9[化学工程—化纤工业] O632.52[理学—高分子化学]