PH-SENSITIVE

作品数：110被引量：192H指数：6
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相关作者：杜启云李国东王薇王素芳吴丽美更多>>
相关机构：东南大学浙江大学教育部吉林大学更多>>
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Targeted and pH-sensitive polyzwitterionic liposomes for oral anticancer drug delivery
《Particuology》2025年第3期13-20,共8页Mingyang Hu Rui Zheng Qi Pan Chen Peng Xinyue Zhang Wei He Wenlong Yao Yan Li 
financially supported by the Fundamental Research Funds for the Central Universities(grant No.06500230,FRF-BR-23-02B);the National Natural Science Foundation of China(grant No.32071391);the Interdisciplinary Research Project for Young Teachers of USTB(Fundamental Research Funds for the Central Universities,FRF-IDRY-23-019);the Beijing Nova Program(grant No.20230484423).
Compared to intravenous injection,oral administration is attractive due to its many advantages for cancer therapy.Taken physiological barriers and other profiles of oral anticancer drug carriers into consideration,tar...
关键词：Polyzwitterionic liposomes Poly(carboxybetaine) Doxorubicin hydrochloride Oral administration Cancer therapy 
Elaborate construction of pH-sensitive polymyxin B loaded nanoparticles for safe and effective treatment of carbapenem-resistant Klebsiella pneumoniae
《Chinese Chemical Letters》2025年第3期402-406,共5页Wen Zhong Dan Zheng Xukun Liao Yadi Zhou Yan Jiang Ting Gao Ming Li Chengli Yang 
supported by the National Natural Science Foundation of China(Nos.81860543,32360237);Guizhou Provincial Science and Technology Projects(Nos.ZK[2024]235,ZK[2023]Key Project 041).
The escalation in the incidence of multidrug-resistant Gram-negative bacteria is becoming a pressing global concern.Polymyxin B(PMB),a conventional antibiotic with notable therapeutic efficacy against Gram-negative ba...
关键词：Polymyxin B pH-sensitive modification Carbapenem-resistant Klebsiella pneumoniae ANTIBACTERIAL Biological security 
A color-changing carbon dots/hydrogel composite for human motion sensing and sweat pH detection
《Nano Research》2025年第2期1-10,共10页Junje Cai Huajiang Hu Jiurong Li Junfei Liao Xiao Gong 
This work was supported by the National Natural Science Foundation of China(No.21774098).
Carbon dots(CDs)are a type of fluorescent nanomaterial that have gained significant attention due to their simple synthesis method and excellent optical properties.The unique structure of CDs also allows for effective...
关键词：carbon dots MULTICOLOR PH-SENSITIVE HYDROGEL motion sensing 
Research on pH-responsive antibacterial materials using citral-modified zinc oxide nanoparticles
《Food Quality and Safety》2024年第4期639-652,共14页Yanan Fan Qixiang Xu Keyu Ren Mengge Zhai Guozheng Xing Yishan Song Yongheng Zhu 
funded by the National Natural Science Foundation of China(No.32272399).
Objectives:With the increasing damage caused by foodborne pathogens to human health and the increasing attention given to healthy diets,novel food antimicrobial agents have been widely studied.Materials and Methods:In...
关键词：Foodborne pathogen STERILIZATION PH-SENSITIVE imine bond food safety 
Efficient and pH-Sensitive Nonconventional Luminescent Polymers for Cellular Imaging and Ion Detection
《Chinese Journal of Polymer Science》2024年第11期1679-1689,I0007,共12页Jiao He Hua-Jian Song Zuo-An Liu Bing-Li Jiang Yong-Yang Gong Wang-Zhang Yuan 
financially supported by the National Natural Science Foundation of China(No.52163017);Project of Guangxi Natural Science Foundation(No.2021GXNSFAA220047);the project of Thousand Outstanding Young Teachers'Training in Higher Education Institutions of Guangxi and the Open Project Program of Guangxi Key Laboratory of Optical and Electronic Materials and Devices(No.20AA-2)。
Nonconventional luminescent materials(NLMs)are a type of organic luminescent materials that does not contain aromatic units.Due to the simplicity of the synthesis process,mild reaction conditions,good hydrophilicity a...
关键词：Clusteroluminescence Nonconventional luminescent materials Dilute solutions Cell imaging 
Remodeling tumor microenvironment using pH-sensitive biomimetic co-delivery of TRAIL/R848 liposomes against colorectal cancer
《Oncology Research》2024年第11期1765-1776,共12页YONGJIAN HUANG JINZHOU WANG JIUHUA XU NING RUAN 
approved by the Institutional Animal Care and Use Committee(IACUC)of the First Affiliated Hospital of Fujian Medical University(No.2023048).
Background:Despite significant advancements in the development of anticancer therapies over the past few decades,the clinical management of colorectal cancer remains a challenging task.This study aims to investigate t...
关键词：Colorectal cancer Plasmid TRAIL(pTRAIL) R848 Tumor-associated macrophages 
A pH-Sensitive I-Motif Aptamer Probe for Dual Targeting and Imaging of Pancreatic Cancer Cells via Nucleolin Interactions
《Journal of Bio-X Research》2024年第3期114-118,共5页Quwen Li Qingquan Chen Juan Tang Qicai Liu Feng Gao 
This work was supported by the National Natural Science Foundation of China(No.82172953);the Fujian Natural Science Foundation(No.2021J01716);the National Key Clinical Specialty Construction Project Fund(No.2022YBL-ZD-02).
This study investigates the targeted imaging and tumor inhibition effects of a"signal-off"imaging-based activatable aptamer probe(I-AAP)for pancreatic cancer.AS1411,contained in the I-AAP probe,targets the nucleolin a...
关键词：dual targeting tumor inhibition pancreatic cancer i motif aptamer phosphate buffer solution targeted imaging ph sensitive 
Codelivery of anti-CD47 antibody and chlorin e6 using a dual pH-sensitive nanodrug for photodynamic immunotherapy of osteosarcoma被引量：3
《Oncology Research》2024年第4期691-702,共12页JIJIE XIAO HONG XIAO YUJUN CAI JIANWEI LIAO JUE LIU LIN YAO SHAOLIN LI 
Osteosarcoma is a malignant tumor originating from bone tissue that progresses rapidly and has a poor patient prognosis.Immunotherapy has shown great potential in the treatment of osteosarcoma.However,the immunosuppre...
关键词：IMMUNOTHERAPY OSTEOSARCOMA Nanodrug Photodynamic therapy CD47 
Yeast-Controlled Double-Shelled CacO_(3)/CaF_(2)Hollow Nanospheres with Hierarchically Porous for Sustained pH-Sensitive Drug Release
《Chinese Journal of Chemistry》2024年第15期1713-1720,共8页Xinhe Liu Yi Chang Guanglei Ma Tingting Liu Penghui Song Heng Yu Xueqing Ren Yuming Guo Xiaoming Ma 
financially supported by the Natural Science Foundation of Henan Province of China(Key Program,No.242300421205);the National Natural Science Foundation of China(21877027,21771058,and 21601052);Key Science and Technology Project of Henan Province(232102310223);Program for Science&Technology Innovation Talents in Universities of Henan Province(No.23HASTITO02);Natural Science Foundation of Henan(212300410009);the Program for Innovative Research Team in Science and Technology in Universities of Henan Province(19IRTSTHNO23).
Hierarchically porous materials(HP materials)are believed one of the most hopeful matrix materials because of their distinctive multimodal pore structures and tremendous application potentials in the field of biomedic...
关键词：Biomimetic synthesis Hierarchically porous Sustained pH-sensitive drug release Antitumor agents Drug delivery Calcium Cancer therapy/Hollow structures 
Erratum to:Balancing efficacy and safety of doxorubicin-loaded albumin nanoparticles utilizing pH-sensitive doxorubicin-fatty acid prodrugs
《Nano Research》2024年第7期6774-6775,共2页Yuanhao Yu Shiyi Zuo Jiaxuan Song Lingxiao Li Tian Liu Jiayu Guo Yaqiao Li Danping Wang Qi Lu Helin Wang Dun Zhou Zhonggui He Xiaohong Liu Bingjun Sun Jin Sun 
The Hoechst and DOX tunnel images of the DOX-C_(22) ANPs group at 4 h in Fig.4(a)were mistakenly used with the neighboring images of DOX-C_(26) ANPs group.The images were corrected as follows to be correspondence with...
关键词：group. utilizing loaded 
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