X-刀治疗脑重要功能区AVMs的疗效及影响因素分析  

Curative effect of X-knife on AVMs in the important cerebral function areas and analysis of factors related to it

作　　者：雷鹏[1] 王钰[1] 鲁春迎[1] 刘奇[1] 

机构地区：[1]兰州军区兰州总医院神经外科,全军脑肿瘤诊治中心,兰州730050

出　　处：《中国临床神经外科杂志》2011年第4期212-213,216,共3页Chinese Journal of Clinical Neurosurgery

摘　　要：目的分析X-刀治疗脑动静脉畸形(AVMs)的效果及影响因素。方法对43例脑重要功能区AVMs患者采用X-刀治疗,平均中心剂量和周边剂量分别为26.9Gy和16.2Gy。术后平均随访时间4.5年。采用CTA、MRA、MRI作为疗效评估手段。结果治疗后8月AVMs病灶开始变小。36例(83.7%)在术后1.5～3年病变血管完全闭塞。1例发生病灶部再出血。治疗前有癫痫发作的31例患者中,26例(83.9%)癫痫消失。结论 X-刀是一种安全、有效治疗AVMs的方法,特别是对于病灶位于脑重要功能区,手术风险极大时,可选择X-刀治疗。Objective To explore the curative effect of X-knife on the arteriovenous malformations （AVMs） in the important cerebral function areas and to analyze the factors related to it.Methods Forty-three patients with AVMs in the important cerebral function areas were treated with X-knife.The mean center dose was 26.9 Gy and marginal dose was 16.2 Gy.The mean time of follow-up was 4.5 years and the curative effects were assessed by MRI,MRA and CTA during the follow up period.Results AVMs began to shrink 8 months after the treatment in all the patients.The total occlusion of all the abnormal vascular nidi were achieved in 36（83.7%） patients.The cerebral hemorrhage occurred again in 1 patient.Seizures were controlled after the treatment in 26（83.9%） of 31 patients with epilepsy before the treatment.Conclusion X-knife is an effective and safe method to treat cerebral AVMs,especially in the important cerebral function areas because the microsurgery for AVMs in the important cerebral function areas is very dangerous.

关 键 词：X-刀 脑动静脉畸形 疗效 并发症 

分 类 号：R743.4[医药卫生—神经病学与精神病学] R815.6[医药卫生—临床医学]