Pyridinium tribromide catalyzed condensation of indoles and aldehydes to form bisindolylalkanes  

作　　者：Qin Yang Zheng Lan Yin Ban Lai Ouyang YiYuan Peng 

机构地区：[1]Key Laboratory of Green Chemistry, Jiangxi Province and College of Chemistry, Jiangxi Normal University, Nanchang 330022, China [2]Key Laboratory of Small Fuctional Organic Molecule, Ministry of Education and College of Life Science, Jiangxi Normal University,Nanchang 330022, China

出　　处：《Chinese Chemical Letters》2011年第5期515-518,共4页中国化学快报（英文版）

基　　金：the National Natural Science Foundation of China(Nos.20862009 and 20962010);the National Natural Science Foundation of Jiangxi Province(No.2008GQH0026);the Science Foundation of Education Department of Jiangxi Province(No.GJJ10386) for their financial support

摘　　要：An efficient synthetic method for bis（indol-3-yl）alkane derivatives has been developed.In the presence of 5 mol%of pyridinium tribromide（PTB）,the condensation of indoles and aldehydes proceeded smoothly under mild conditions,giving rise to the corresponding bis（indol-3-yl）alkanes in good to excellent yields.An efficient synthetic method for bis（indol-3-yl）alkane derivatives has been developed.In the presence of 5 mol%of pyridinium tribromide（PTB）,the condensation of indoles and aldehydes proceeded smoothly under mild conditions,giving rise to the corresponding bis（indol-3-yl）alkanes in good to excellent yields.

关 键 词：Pyridinium tribromide INDOLE ALDEHYDE Bis（indol-3-yl）alkane 

分 类 号：O626.13[理学—有机化学] TQ655[理学—化学]