影响肝门部胆管癌预后的病理学因素研究  

Affect the prognosis of hilar bile pathological factors

作　　者：曹清 

机构地区：[1]江西省九江市第三人民医院,江西九江332000

出　　处：《中国医药导报》2011年第15期41-42,共2页China Medical Herald

摘　　要：目的:探讨肝门部胆管癌病理组织学特征与预后的关系。方法:回顾性分析1998年3月～2006年10月我院收治的128例肝门部胆管癌患者的临床资料,分析患者预后与病理组织学特征的关系。结果:128例肝门部胆管癌中高、中分化腺癌淋巴结转移率和肝转移率明显低于低分化腺癌转移率(P<0.05)。高、中分化腺癌和低分化腺癌术后1、3、5年生存率比较,高、中分化腺癌生存率明显高于低分化腺癌(P<0.05)。结论:低分化腺癌在肝门部胆管癌的病理分型中占有相当大的比例,并且病理的分化程度与肿瘤的侵袭能力和预后关系密切。Objective：To research into the relationship between the histopathology characteristics and prognosis of hilar cholangiocarcinoma.Methods：Retrospectively analyze the clinical data of 128 hilar cholangiocarcinoma patients treated at our hospital from March 1998 to October 2006,and analyze the relationship between the patients＇ prognosis and the histopathology characteristics of their tissues.Results：Among the 128 cases of hilar cholangiocarcinoma,the lymph node metastatic rate and liver metastatic rate of well differentiated and middle differentiated adenocarcinoma were significantly lower than the metastatic rate of poorly differentiated adenocarcinoma（P0.05）.When comparing the survival rates of well differentiated and middle differentiated adenocarcinoma and poorly differentiated adenocarcinoma at 1 year,3 years and 5 years respectively after operation,the survival rates of well differentiated and middle differentiated adenocarcinoma were significantly higher than those of poorly differentiated adenocarcinoma（P0.05）.Conclusion：Poorly differentiated adenocarcinoma accounts for a large proportion of pathological classification of hilar cholangiocarcinoma,and there is close relationship between pathological differentiation and the invasioness and prognosis of tumor.

关 键 词：肝门部胆管癌 生存率 病理组织学 

分 类 号：R730.21[医药卫生—肿瘤]