上感颗粒对病毒性上呼吸道感染患者体温的影响  

Effect of Shanggan Granules on Fever Caused by Upper Respiratory Tract Viral Infection

作　　者：奚肇庆[1] 余衍亮[1] 刘清泉[2] 张晓云[3] 罗翌 张念志[5] 孙伯青[6] 孙菊光 杜梁枫 郑艳[9] 卜擎燕[1] 邹建东[1] 芮庆林[1] 张丽[9] 刘夕宁[9] 曾亮[9] 耿连艺[9] 熊宁宁[1] 

机构地区：[1]江苏省中医院,南京210029 [2]北京中医药大学附属东直门医院,北京100700 [3]成都中医药大学附属医院,成都610072 [4]广州中医药大学第二附属医院,广州510120 [5]安徽中医学院附属医院,合肥215300 [6]昆山市中医医院,江苏昆山215300 [7]徐州市中医院,江苏徐州221003 [8]无锡市中西医结合医院,江苏无锡214000 [9]南京中医药大学,南京210029

出　　处：《中药新药与临床药理》2011年第3期349-352,共4页Traditional Chinese Drug Research and Clinical Pharmacology

基　　金：国家中医药行业专项科研基金(200807041)

摘　　要：目的评价透表清气法(上感颗粒)对病毒性上呼吸道感染性发热的作用。方法采用多中心研究方法,观察上感颗粒对433例不同证型的病毒性上呼吸道感染性发热的即刻退热作用、起效时间和退热时间。结果上感颗粒的起效时间为2.35 h,4 h内体温下降≥0.5℃的患者例数占50%左右,平均退热时间为13.55 h,72 h内体温恢复正常者占93%。结论上感颗粒治疗上呼吸道病毒感染性发热的各证型均有较好的临床疗效。Objective To evaluate the effect of Shanggan Granules,a representative prescription of the therapy of relieving the exterior syndrome and reducing heat,on the fever caused by upper respiratory tract viral infection.Methods We adopted the cohort and multi-center study.The instant antipyretic effect,the effect-acting antipyretic time,and the final antipyretic time were analyzed in 433 cases with different clinical syndromes.Results In average,the effect-acting antipyretic time was 2.35 hours,the rate of temperature drop more than 0.5 ℃ within 4 h was about 50 %,the final antipyretic time was 13.55 hours,and the rate of temperature dropping to the normal within 72 h was 93 %.Conclusion Shanggan Granules has certain effect on the fever caused by upper respiratory tract viral infection in patients with various syndromes.

关 键 词：透表清气法 上感颗粒 病毒性上呼吸道感染 外感发热 

分 类 号：R285.6[医药卫生—中药学]