多层CT灌注成像在胸腺疾病中的临床应用  

CT perfusion imaging in the diagnosis of thymus disease

作　　者：郭红娟[1] 郭君武[1] 

机构地区：[1]郑州大学第二附属医院CT室,450003

出　　处：《中国实用医刊》2011年第11期20-21,共2页Chinese Journal of Practical Medicine

摘　　要：目的评价CT灌注成像对良性胸腺瘤、恶性胸腺瘤、残余胸腺的诊断价值。方法45例患者行多层螺旋cT胸腺灌注检查，其中恶性胸腺瘤10例，良性胸腺瘤20例，残余胸腺15例。采用GE light speed4排多层螺旋CT机扫描，应用随机功能软件分析图像，测量良恶性胸腺瘤、残余胸腺的血流量（BF）、血容量（BV）、平均通过时间（MTT）、表面通透性（PS），并运用统计学对此进行分析，探讨良性胸腺瘤与恶性胸腺瘤、良性胸腺瘤与残余胸腺之间的区别。结果BV、MTT在恶性、良性及残余胸腺之间比较差异有统计学意义（P〈0．05）。PS在恶性胸腺瘤、良性胸腺瘤及残余胸腺间比较差异有统计学意义（P〈0．01）。结论螺旋CT灌注成像可精确反映不同时闯段病变的强化特征，根据病变内不同的血流学改变，更准确的鉴别恶性胸腺瘤、良性胸腺瘤及残余胸腺。Objective To assess the value of CT perfusion lesion, malignant thymus lesion and residual thymus. Methods imaging in diagnosis of benign thymus Forty- five cases of the thymus were examined by CT perfusion, malignant thymus lesion 10 cases, benign thymus lesion 20 cases and residual thymus 15 cases. Use GE light speed plus 4 - slice CT perfusion imaging and analysis by the stochastic analysis software. Measure tbe blood flow （BF）, blood volume（ BV）, mean transit time （MTlP） and permeability surface （PS） of benign thymus lesion, malignant thymus lesion and residual thymus and analysis by statistics. To explore the difference between benign thymus lesion and malignant thymus lesion, residual thymus. Results BV and MTF had significant differences among benign thymus lesion, malignant thymus lesion and residual thymus （P 〈 0. 05）. PS had the highly significant difference among benign thymus lesion, malignant thymus lesion and residual thymus （P 〈 0.01 ）. Conclusions CT can accurately reflect the strengthening characteristics of each time lesions. According to the changing of lesions blood flow, it can accurately differentiate benign thymus lesion, malignant thymus lesion and residual thymus.

关 键 词：胸腺瘤 CT灌注成像 体层摄影技术 

分 类 号：R730[医药卫生—肿瘤] R816[医药卫生—临床医学] R5