早产儿视网膜病变的筛查分析  

Analysis of screening results ofretinopathy ofprematurity

作　　者：马萍萍[1] 张秋玲[1] 张敏[1] 李达桔[1] 陈敏瑜[1] 

机构地区：[1]东莞市人民医院眼科,广东东莞523018

出　　处：《中国实用眼科杂志》2011年第5期509-511,共3页Chinese Journal of Practical Ophthalmology

基　　金：东莞市重点科技计划项目（200910515023）

摘　　要：目的 了解早产儿视网膜病变（retinopathy of prematurity,ROP）发病情况.方法 回顾性分析2009年6月至2010年10月间在东莞市人民医院ROP发病率及其特点.结果 接受筛查的早产儿共126例,发生ROP病变的21例,均为双眼发病,发病率16.67%,未到阈值前病变的19例,发病率15.08%,阈值病变2例,发病率1.59%.其中出生体重〈1500g的41例,ROP病变患儿13例,发病率为31.71%,1500g≤出生体重〈2000g的85例,ROP病变患儿8例,发病率为9.41%;出生孕周〈32周的49例,ROP患儿15例,发病率30.61%,出生孕周≥32周的77例,ROP患儿6例,发病率7.79%.出生体重〈1500g和1500g≤出生体重〈2000g两组患儿发病率比较（x2=9.899,P〈0.01）、出生孕周〈32周和出生孕周≥32周的两组患儿发病率分别比较（x2=11.227,P〈0.01）,差异均具有统计学意义.结论 ROP发病率为16.67%,危及患儿视力的严重ROP发病率低,低出生体重与低出生孕周是影响ROP发病的重要因素.Objective To investigate the incidence of retinopathy of prematurity（ROP）in Dongguan People＇s Hospital. Methods Records of premature infants who had undergone ROP screening in our hospital between June 2009 and October 2010 were analyzed retrospectively. Results Twenty-one cases out of 126 screened infants had developed ROP. Both eyes suffered from ROP in all the cases. The incidence of ROP was 16.67%. Of 19 cases（15.08%）developed ROP less than prethreshold and 2 cases（1.59%）developed threshold ROP. Among the 126 screened infants, 13（31.71%）out of 41 premature infants with birth weight（BW）〈1500g and 8（9.41%）out of 85 with 1500g≤BW〈2000g developed ROP, 15（30.61%）out of 49 with gestational age （GA）〈32W and 6（7.79%）out of 77 with GA≥ 32W developed ROP. The incidence of ROP either among the groups of BW〈1500g andl500g≤BW〈2000g（x2=9.899, P 〈0.01）, or among the groups of GA〈32W and GA≥32W（x2=11.227, P〈0.01）had statistical differences. Conclusions The incidence of ROP is 16.67% in Dongguan People＇s Hospital in present study. The incidence of severe ROP is low. Birth weight and gestational age are important factors to affect ROP incidence.

关 键 词：视网膜病 早产儿 流行病学 视网膜病 早产儿/病因学 视网膜病 早产儿/诊断 新生儿筛查 

分 类 号：R774.1[医药卫生—眼科]