SPECT／CT同机融合显像检测鼻咽癌侵犯颅底骨的临床价值  

Early Detecting Value of SPECT/CT Fusion Imaging in Skull Base Bone Invasion of Nasopharyngeal Carcinoma

作　　者：葛永斌[1] 徐卫平[2] 刘枫[1] 任志刚[1] 刘致俊[1] 刘淑华[1] 

机构地区：[1]广州医学院附属肿瘤医院核医学科,广东广州510095 [2]广东省人民医院核医学科

出　　处：《解剖与临床》2011年第2期114-117,共4页Anatomy and Clinics

摘　　要：目的：探讨SPECT／CT同机融合显像对鼻咽癌颅底骨侵犯早期检测的临床价值。方法：对60例鼻咽癌初诊患者，进行全身前后位SPECT骨显像、CT扫描和SPECT／CT同机融合显像，由两位核医学科医生共同做出诊断，对结果进行对比分析。结果：鼻咽癌颅底骨侵犯SPECT阳性检出率46．7％（28／60），CT阳性检出率28．3％（17／60），SPECT／CT同机融合显像阳性检出率55．0％（33／60）。SPECT／CT同机融合显像对颅底骨侵犯的阳性检出率与SPECT相比，差异无统计学意义（P〉0．05）；颅底骨侵犯SPECT／CT同机融合显像的阳性检出率高于CT，差异有统计学意义（P〈0．05）。结论：SPECT／CT同机融合显像对鼻咽癌颅底骨侵犯检测敏感性与单纯SPECT检查相比无明显差异，但明显高于CT，对鼻咽癌颅底骨侵犯早期检测有一定临床价值。Objective：To investigate the early detecting value of SPECT/CT fusion imaging in skull base bone invasion of uasopharyngeal carcinoma. Methods： Sixty patients with newly diagnosed nasopharyngeal carcinoma were examined by SPECT/CT fusion imaging , SPECT and CT in skull base. The patients were diagnosed by two experienced doctors from nuclear department; the results were compared and evaluated. Results：The overall positive rate of skull base bone invasion detected by SPECT was 46.7% （28/60）. The positive rate of CT was 28.3% （17/60）. The positive rate of SPECT/CT fusion imaging was 55.0% （ 33/60 ）, it was obviously higher than that by CT （ McNemar Test, P 〈 0.05 ）. There was no significant difference among the detective results of whole bone SPECT and SPECT/CT fusion imaging （ P 〉 0.05 ）. The positive rate of skull base bone invasion detected by SPECT/CT fusion imaging was higher than that by CT, there was statistical significance （ P 〈 0.05 ）. Conclusions ： There was no significant difference between the detective results of detection sensitivity by SPECT/CT fusion imaging and by SPECT alone, but obviously higher than that by CT. There are some clinical values of SPECT/CT fusion imaging in skull base bone invasion of nasopharyngeal carcinoma.

关 键 词：鼻咽癌 颅底骨侵犯 SPECT/CT融合显像 SPECT CT 

分 类 号：R730.44[医药卫生—肿瘤] R739.63[医药卫生—临床医学]